The relationship between frailty, nutritional status, co-morbidity, CT-body composition and systemic inflammation in patients with COVID-19

J McGovern, Y Al-Azzawi, O Kemp, P Moffitt… - Journal of translational …, 2022 - Springer
Background Frailty, determined by the Canadian Study of Health and Aging-Clinical Frailty
Scale (CFS), is strongly associated with clinical outcomes including mortality in patients with …

Association between Clinical Frailty Scale (CFS) and clinical presentation and outcomes in older inpatients with COVID-19

A Martí-Pastor, O Moreno-Perez, E Lobato-Martínez… - BMC geriatrics, 2023 - Springer
Background Frailty is a physiological condition characterized by a decreased reserve to
stressors. In patients with COVID-19, frailty is a risk factor for in-hospital mortality. The aim of …

[HTML][HTML] The impact of frailty on COVID-19 outcomes: a systematic review and meta-analysis of 16 cohort studies

Y Yang, K Luo, Y Jiang, Q Yu, X Huang, J Wang… - The Journal of nutrition …, 2021 - Elsevier
Background Frail patients are increasingly vulnerable to stress, which is mainly manifested
by a reduced physiologic reserve in metabolic and immune systems and neuromuscular …

Clinical frailty scale as a point of care prognostic indicator of mortality in COVID-19: a systematic review and meta-analysis

S Kastora, G Kounidas, S Perrott, B Carter… - …, 2021 - thelancet.com
Background COVID-19 has resulted in the largest pandemic experienced since 1918,
accounting for over 2 million deaths globally. Frail and older people are at the highest risk of …

Clinical frailty score as an independent predictor of outcome in COVID-19 hospitalised patients

G Koduri, S Gokaraju, M Darda, V Warrier… - European Geriatric …, 2021 - Springer
Purpose of the study We explored potential predictive variables associated with outcomes
using baseline clinical parameters of 500 hospitalised patients with COVID-19 in a single …

The devastating trio of sarcopenia, frailty, and COVID-19-A systematic review and meta-analysis

H Halaweh, I Ghannam - Clinical Nutrition ESPEN, 2022 - Elsevier
Background & aims Sarcopenia, frailty, and COVID-19 appear to be intertwined. Preventive
and intervention measures are required to break this link and mitigate the consequences of …

The value of clinical frailty scale (CFS) as a prognostic tool in predicting mortality in COVID-19—a retrospective cohort study

M Jachymek, A Cader, M Ptak, W Witkiewicz… - International Journal of …, 2022 - mdpi.com
Background: Due to the unpredictable nature of COVID-19, there is a need to identify
patients at high risk of severe course of the disease and a higher mortality rate. Objective …

Frailty and mortality in hospitalized older adults with COVID-19: retrospective observational study

R De Smet, B Mellaerts, H Vandewinckele… - Journal of the American …, 2020 - Elsevier
Objectives To determine the association between frailty and short-term mortality in older
adults hospitalized for coronavirus disease 2019 (COVID-19). Design Retrospective single …

Frailty and mortality associations in patients with COVID‐19: a systematic review and meta‐analysis

A Subramaniam, K Shekar, A Afroz… - Internal Medicine …, 2022 - Wiley Online Library
Background Observational data during the pandemic have demonstrated mixed
associations between frailty and mortality. Aim To examine associations between frailty and …

The effect of frailty on in-hospital and medium-term mortality of patients with COronaVIrus Disease-19: the FRACOVID study.

P Rebora, E Focà, A Salvatori, A Zucchelli… - Panminerva …, 2021 - europepmc.org
Background Older people hospitalized for COVID-19 are at highest risk of death. Frailty
Assessment can detect heterogeneity in risk among people of the same chronological age …