Characterization of the therapeutic profile of albiflorin for the metabolic syndrome

X Zhou, S Fouda, XY Zeng, D Li, K Zhang… - Frontiers in …, 2019 - frontiersin.org
Albiflorin (AF) is a small molecule (MW 481) isolated from Paeoniae radix, a plant used as a
remedy for various conditions with pathogenesis shared by metabolic diseases. Reported …

Ellagic acid affects metabolic and transcriptomic profiles and attenuates features of metabolic syndrome in adult male rats

A Kábelová, H Malínská, I Marková, O Oliyarnyk… - Nutrients, 2021 - mdpi.com
Ellagic acid, a natural substance found in various fruits and nuts, was previously shown to
exhibit beneficial effects towards metabolic syndrome. In this study, using a genetic rat …

Astragalin mediates the pharmacological effects of Lysimachia candida Lindl on adipogenesis via downregulating PPARG and FKBP51 signaling cascade

S Barge, B Deka, B Kashyap, S Bharadwaj… - Phytotherapy …, 2021 - Wiley Online Library
Metabolic disturbances in different tissue cells and obesity are caused by excessive calorie
intake, and medicinal plants are potential sources of phytochemicals for combating these …

Albiflorin ameliorates obesity by inducing thermogenic genes via AMPK and PI3K/AKT in vivo and in vitro

MY Jeong, J Park, DH Youn, Y Jung, JW Kang, S Lim… - Metabolism, 2017 - Elsevier
Objective Brown adipose tissue (BAT) activation has been identified as a possible target to
treat obesity and to protect against metabolic diseases by increasing energy consumption …

A Multitarget Approach to Evaluate the Efficacy of Aquilaria sinensis Flower Extract against Metabolic Syndrome

HS Chae, O Dale, TM Mir, B Avula, J Zhao, IA Khan… - Molecules, 2022 - mdpi.com
Aquilaria sinensis (Lour.) Spreng is known for its resinous secretion (agarwood), often
secreted in defense against injuries. We investigated the effects of A. sinensis flower extract …

Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle

A Leber, R Hontecillas, N Tubau-Juni… - Scientific Reports, 2020 - nature.com
Abscisic acid is a phytohormone found in fruits and vegetables and is endogenously
produced in mammals. In humans and mice, lanthionine synthetase C-like 2 (LANCL2) has …

Amorphastilbol exerts beneficial effects on glucose and lipid metabolism in mice consuming a high-fat-diet

W Lee, J Ham, HC Kwon, G Yoon… - International …, 2015 - spandidos-publications.com
In the present study, the anti-diabetic effects of amorphastilbol (APH) from Amorpha fruticosa
(AF) were evaluated in high‑fat‑diet (HFD) mice. HFD‑induced blood glucose and insulin …

Paeoniflorin protects against nonalcoholic fatty liver disease induced by a high-fat diet in mice

L Zhang, B Yang, B Yu - Biological and pharmaceutical bulletin, 2015 - jstage.jst.go.jp
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide. Paeoniflorin, a natural product and active ingredient of Paeonia lactiflora, has …

Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats

Z Ma, L Chu, H Liu, W Wang, J Li, W Yao, J Yi, Y Gao - Scientific reports, 2017 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver
diseases. This study sought to evaluate the insulin-sensitizing effect of paeoniflorin (PF) on …

[HTML][HTML] Anti-adipogenic effect of alchemilla monticola is mediated via PI3K/AKT signaling inhibition in human adipocytes

SG Mladenova, LV Vasileva, MS Savova… - Frontiers in …, 2021 - frontiersin.org
Obesity is a persistent and continuously expanding social health concern. Excessive fat
mass accumulation is associated with increased risk of chronic diseases including diabetes …