Previously, we have reported that consumption of a muscadine grape phytochemical
powder (MGP) decreased lipid accumulation in high-fat fed mice. The aim of this study was …

To determine the effects of nordihydroguaiaretic acid (NDGA) on metabolic and molecular
changes in response to feeding a typical American fast food or Western diet, mice were fed …

Albiflorin, a principal monoterpene glycoside isolated from Paeonia lactiflora Pall., is known
for its extensive pharmacological properties and medicinal value in a number of traditional …

This study aimed to examine the protective effect of Artemisia iwayomogi extract (AI) against
hypertriglyceridemia induced by a high-fat diet (HFD) in mice and to uncover the underlying …

Scope Olive-tree polyphenols have demonstrated potential for the management of obesity-
related pathologies. We aimed to explore the capacity of Olive-tree leaves extract to …

Background Nutrient overload predisposes the development of metabolic dysfunction-
associated fatty liver disease (MAFLD). However, there are no specific pharmacological …

The global morbidity of obesity and type 2 diabetes mellitus (T2DM) has dramatically
increased. Insulin resistance is the most important pathogenesis and therapeutic target of …

In our previous study, a derivative of tiliroside, 3-O-[(E)-4-(4-ethoxyphenyl)-2-oxobut-3-en-1-
yl] kaempferol (Fla-OEt) significantly enhanced glucose consumption in insulin resistant …

Several in vitro and in vivo studies have reported the anti-inflammatory, anti-diabetic and
anti-obesity effects of the flavonoid apigenin. However, the long-term supplementary effects …

Non-alcoholic fatty liver disease (NAFLD) affects approximately a quarter of the population
and, to date, there is no approved drug therapy for this condition. Individuals with type 2 …