[HTML][HTML] Causes and consequences of HPV integration in head and neck squamous cell carcinomas: state of the art

H Balaji, I Demers, N Wuerdemann, J Schrijnder… - Cancers, 2021 - mdpi.com
Simple Summary In human papillomavirus (HPV) associated head and neck squamous cell
carcinomas (HNSCC) s, the HPV genome is commonly found integrated in the human …

HPV integration in head and neck squamous cell carcinomas: cause and consequence

EJM Speel - HPV infection in head and neck cancer, 2017 - Springer
Human papillomaviruses (HPVs) are a necessary cause of anogenital squamous cell
carcinomas (SCC) and a subgroup of head and neck SCC, ie, those originating in the …

Human papillomavirus genome integration and head and neck cancer

LM Pinatti, HM Walline… - Journal of dental …, 2018 - journals.sagepub.com
We conducted a critical review of human papillomavirus (HPV) integration into the host
genome in oral/oropharyngeal cancer, reviewed the literature for HPV-induced cancers, and …

Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma

J Mainguené, S Vacher, M Kamal, A Hamza… - Molecular …, 2022 - Wiley Online Library
A prevalence of around 26% of human papillomavirus (HPV) in head and neck squamous
cell carcinoma (HNSCC) has been previously reported. HPV induced oncogenesis mainly …

[HTML][HTML] Long-read sequencing of oropharyngeal squamous cell carcinoma tumors reveal diverse patterns of high-risk Human Papillomavirus integration

MA Gauthier, A Kadam, G Leveque, N Golabi… - Frontiers in …, 2023 - frontiersin.org
Introduction In North America and in most European countries, Human Papillomavirus (HPV)
is responsible for over 70% of oropharyngeal squamous cell carcinomas. The burden of …

Identification of human papillomavirus (HPV) 16 DNA integration and the ensuing patterns of methylation in HPV‐associated head and neck squamous cell carcinoma …

T Hatano, D Sano, H Takahashi… - … journal of cancer, 2017 - Wiley Online Library
Recent studies showed that human papillomavirus (HPV) integration contributes to the
genomic instability seen in HPV‐associated head and neck squamous cell carcinoma (HPV …

Characterization of HPV and host genome interactions in primary head and neck cancers

M Parfenov, CS Pedamallu… - Proceedings of the …, 2014 - National Acad Sciences
Previous studies have established that a subset of head and neck tumors contains human
papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display …

Genomic characterization of viral integration sites in HPV‐related cancers

C Bodelon, ME Untereiner, MJ Machiela… - … journal of cancer, 2016 - Wiley Online Library
Persistent infection with carcinogenic human papillomaviruses (HPV) causes the majority of
anogenital cancers and a subset of head and neck cancers. The HPV genome is frequently …

Analysis of the integration of human papillomaviruses in head and neck tumours in relation to patients' prognosis

Z Vojtechova, I Sabol, M Salakova… - … journal of cancer, 2016 - Wiley Online Library
Integration, which leads to the disruption of the circular HPV genome, is considered as a
critical, albeit not obligatory, step in carcinogenic progression. Although cervical carcinomas …

Human papillomavirus genome integration in squamous carcinogenesis: what have next‐generation sequencing studies taught us?

IJ Groves, N Coleman - The Journal of pathology, 2018 - Wiley Online Library
Human papillomavirus (HPV) infection is associated with∼ 5% of all human cancers,
including a range of squamous cell carcinomas. Persistent infection by high‐risk HPVs …