It has been shown that stimulation-produced-analgesia (SPA) in the cat elicited from the
periaqueductal gray matter (PAG) is obtained from sites located in the ventral part …

This study consists of a detailed analysis of the analgesic effects induced by stimulation of
the various parts of the periaqueductal gray matter (PAG) in the freely moving rat. In order to …

Many psychological and environmental factors are known to influence responsiveness to
noxious sensory stimuli. Until recently, the physiological mechanisms which enable such …

1. To obtain a comprehensive map of the ascending projection of the midbrain
periaqueductal gray, small amounts of [3H] leucine were injected into discrete regions of the …

Both electrical stimulation and injection of morphine into the midbrain periaqueductal gray
(PAG) produce analgesia in the rat. There is evidence that this analgesic effect is mediated …

Since Reynold's initial report years ago (1969) revealed that during and after periaqueductal
gray matter (PAG) stimulation rats could support severe, painful interventions such as …

Pentobarbital-anesthetized rats were subjected to 21 min of continuous electrical stimulation
of the caudal periaqueductal gray matter (PAG) at the current threshold for analgesia …

These studies investigated the distribution of analgesia-producing sites within the
periaqueductal gray (PAG), and their potential reversal by naloxone and methysergide. The …

Over two decades ago it was discovered that electrical stimulation of the periaqueductal
gray (PAG) caused profound analgesia (Reynolds, 1969). It was subsequently found that …

Potent analgesia results from electrical stimulation of the periaqueductal gray matter (PGM)
in the cat 1, 14 as in the rat 11, 12, 16. In the cat, these effects are preferentially evoked from …