Objective: To review the mechanisms of metabolic acidosis in sepsis. Data sources: Articles
and published reviews on metabolic acidosis in sepsis. Summary of review: Sepsis affects …

Metabolic acidosis is very common in critically ill septic patients. Acidosis may be a result of
the underlying pathophysiology, but it also may be the result of the way in which those …

Objective: To describe the composition of metabolic acidosis in patients with severe sepsis
and septic shock at intensive care unit admission and throughout the first 5 days of intensive …

Aims: To describe at Intensive Care Unit (ICU) admission and over the first 5 days the
composition of metabolic acidosis in patients with sepsis and to evaluate and compare …

Objective: To quantitate the contribution of lactate, phosphate, urate, total serum proteins,
and unidentified anions to the anion gap in patients with severe sepsis. Design: Thirty …

Metabolic acidosis is among the most common abnormalities seen in patients suffering from
critical illness. Its etiologies are multiple and treatment of the underlying condition is the …

Lactic acidosis is a common finding in critically ill patients during severe sepsis/septic shock,
and a powerful predictor of mortality. Because of the knowledge that lactate is the end …

Acid-base abnormalities are extremely common in modern ICUs. Although most cases are
mild and self-limiting, there are certain circumstances in which acid-base derangements are …

Mortality on the intensive care unit is high, particularly due to sepsis and multiple organ
failure. Inadequate oxygen delivery secondary to poor perfusion may underlie organ …

Unlike most other aspects of critical care medicine, the management of metabolic
dysfunction has not seen any major innovations in many years. Although acid-base …