[HTML][HTML] Low-density lipoprotein receptors play an important role in the inhibition of prostate cancer cell proliferation by statins
Y Furuya, Y Sekine, H Kato, Y Miyazawa, H Koike… - Prostate …, 2016 - Elsevier
Background There are some reports about the antitumor effects of statins in these days.
Statins decrease the level of cholesterol in the blood by inhibiting 3-hydroxy-3-methylglutaryl …
Statins decrease the level of cholesterol in the blood by inhibiting 3-hydroxy-3-methylglutaryl …
Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL
TJ Murtola, H Syvälä, P Pennanen, M Bläuer… - European journal of …, 2011 - Elsevier
Epidemiological studies have linked statin use with a decreased risk of advanced prostate
cancer and an improved recurrence-free survival after radical therapy. It is unclear, however …
cancer and an improved recurrence-free survival after radical therapy. It is unclear, however …
Dyslipidemia, statins and prostate cancer
KR Rice, MO Koch, L Cheng… - Expert review of …, 2012 - Taylor & Francis
Dyslipidemia and prostate cancer are two of the most common medical conditions affecting
adult males in the USA. In recent years, a large volume of research has focused on …
adult males in the USA. In recent years, a large volume of research has focused on …
[HTML][HTML] The importance of LDL and cholesterol metabolism for prostate epithelial cell growth
TJ Murtola, H Syvälä, P Pennanen, M Bläuer… - PloS one, 2012 - journals.plos.org
Cholesterol-lowering treatment has been suggested to delay progression of prostate cancer
by decreasing serum LDL. We studied in vitro the effect of extracellular LDL-cholesterol on …
by decreasing serum LDL. We studied in vitro the effect of extracellular LDL-cholesterol on …
Statins and prostate cancer prevention: where we are now, and future directions
TJ Murtola, T Visakorpi, J Lahtela, H Syvälä… - Nature Clinical Practice …, 2008 - nature.com
Statins are cholesterol-lowering drugs that are widely used to prevent and treat
atherosclerotic cardiovascular disease. Recent research from both in vitro and in vivo …
atherosclerotic cardiovascular disease. Recent research from both in vitro and in vivo …
Do the cholesterol-lowering properties of statins affect cancer risk?
KR Solomon, MR Freeman - Trends in Endocrinology & Metabolism, 2008 - cell.com
The potential of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors ('statins') to
reduce the incidence and/or progression of certain malignancies remains uncertain. Some …
reduce the incidence and/or progression of certain malignancies remains uncertain. Some …
Statins: protectors or pretenders in prostate cancer?
H Moon, MM Hill, MJ Roberts, RA Gardiner… - Trends in Endocrinology …, 2014 - cell.com
The role of statin therapy in prostate cancer (PCa) prevention and treatment is plagued by
controversy. This critical review of published clinical series reveals several caveats in earlier …
controversy. This critical review of published clinical series reveals several caveats in earlier …
Rationale for statins in the chemoprevention of prostate cancer
RJ Hamilton, SJ Freedland - Current Prostate Reports, 2008 - Springer
The potential ability of statin medications to prevent cancer has recently received
considerable attention. Of all cancers studied, data for prostate cancer are the most …
considerable attention. Of all cancers studied, data for prostate cancer are the most …
[HTML][HTML] LDL-lowering therapy and the risk of prostate cancer: a meta-analysis of 6 randomized controlled trials and 36 observational studies
The role of statins in preventing prostate cancer is currently a controversial issue. The aim of
this review is to investigate the effects of statins use on prostate cancer risk. Electronic …
this review is to investigate the effects of statins use on prostate cancer risk. Electronic …
Statin use in prostate cancer: an update
MA Babcook, A Joshi, JA Montellano… - Nutrition and …, 2016 - journals.sagepub.com
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, known as statins, are
commonly prescribed for the treatment of hypercholesterolemia and cardiovascular disease …
commonly prescribed for the treatment of hypercholesterolemia and cardiovascular disease …