Achieving 80% ten‐fold cross‐validated accuracy for secondary structure prediction by large‐scale training
An integrated system of neural networks, called SPINE, is established and optimized for
predicting structural properties of proteins. SPINE is applied to three‐state secondary …
predicting structural properties of proteins. SPINE is applied to three‐state secondary …
Combining prediction of secondary structure and solvent accessibility in proteins
Owing to the use of evolutionary information and advanced machine learning protocols,
secondary structures of amino acid residues in proteins can be predicted from the primary …
secondary structures of amino acid residues in proteins can be predicted from the primary …
Context-based features enhance protein secondary structure prediction accuracy
We report a new approach of using statistical context-based scores as encoded features to
train neural networks to achieve secondary structure prediction accuracy improvement. The …
train neural networks to achieve secondary structure prediction accuracy improvement. The …
Real‐SPINE: An integrated system of neural networks for real‐value prediction of protein structural properties
Proteins can move freely in three‐dimensional space. As a result, their structural properties,
such as solvent accessible surface area, backbone dihedral angles, and atomic distances …
such as solvent accessible surface area, backbone dihedral angles, and atomic distances …
SPINE X: improving protein secondary structure prediction by multistep learning coupled with prediction of solvent accessible surface area and backbone torsion …
Accurate prediction of protein secondary structure is essential for accurate sequence
alignment, three‐dimensional structure modeling, and function prediction. The accuracy of …
alignment, three‐dimensional structure modeling, and function prediction. The accuracy of …
Application of multiple sequence alignment profiles to improve protein secondary structure prediction
The effect of training a neural network secondary structure prediction algorithm with different
types of multiple sequence alignment profiles derived from the same sequences, is shown to …
types of multiple sequence alignment profiles derived from the same sequences, is shown to …
EVA: large‐scale analysis of secondary structure prediction
EVA is a web‐based server that evaluates automatic structure prediction servers
continuously and objectively. Since June 2000, EVA collected more than 20,000 secondary …
continuously and objectively. Since June 2000, EVA collected more than 20,000 secondary …
[HTML][HTML] Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure information
Background Structural properties of proteins such as secondary structure and solvent
accessibility contribute to three-dimensional structure prediction, not only in the ab initio …
accessibility contribute to three-dimensional structure prediction, not only in the ab initio …
Redefining the goals of protein secondary structure prediction
Secondary structure prediction recently has surpassed the 70% level of average accuracy,
evaluated on the single residue states helix, strand and loop (Q 3). But the ultimate goal is …
evaluated on the single residue states helix, strand and loop (Q 3). But the ultimate goal is …
Improving the prediction accuracy of residue solvent accessibility and real‐value backbone torsion angles of proteins by guided‐learning through a two‐layer neural …
This article attempts to increase the prediction accuracy of residue solvent accessibility and
real‐value backbone torsion angles of proteins through improved learning. Most methods …
real‐value backbone torsion angles of proteins through improved learning. Most methods …