Atopic asthma pathogenesis is driven by the combined effects of airway inflammation
generated during responses to viral infections and aeroallergens, and both these pathways …

Dendritic cells (DCs) are crucial in determining the outcome of antigen encounter and
integrating signals derived from the antigen, its inflammatory context, and the host …

Dendritic cells (DC) are potent antigen presenting cells that display an extraordinary
capacity to present antigen to naïve T‐cells and initiate primary immune responses. In the …

Airway epithelial cells (AEC) and dendritic cells (DC) are situated in close proximity within
the airway epithelium, and are the first cells to encounter inhaled pathogens, allergens and …

Increasing evidence points to the role of antigen-presenting dendritic cells (DC) in regulating
adaptive immune responses. DC are especially sensitive to signals derived from microbes …

Increasing evidence suggests that crosstalk between airway epithelial cells (AEC) and
adjacent dendritic cells (DC) tightly regulates airway mucosal DC function in steady state …

The airway mucosal response to allergen in asthma involves influx of activated T helper type
2 cells and eosinophils, transient airflow obstruction, and airways hyperresponsiveness …

Airway mucosal dendritic cells (AMDC) and other airway APCs continuously sample inhaled
Ags and regulate the nature of any resulting T cell-mediated immune response. Although …

To cite this article: Hammad H, Lambrecht BN. Dendritic cells and airway epithelial cells at
the interface between innate and adaptive immune responses. Allergy 2011; 66: 579–587 …

Dendritic cells (DCs) initiate and maintain adaptive T helper 2 (Th2) cell responses to
inhaled allergens in asthma. Various functions like antigen uptake, migration to the draining …