[HTML][HTML] Glycyrrhizic acid improves lipid and glucose metabolism in high-sucrose-fed rats

C Chandramouli, YS Ting, LY Lyn, TS Ha… - Journal of Endocrinology …, 2011 - jofem.org
Background: The alarming increase in sugar consumption worldwide has largely contributed
towards the escalating symptoms of metabolic syndrome (MetS) such as obesity, insulin …

[HTML][HTML] Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats

CHA Eu, WYA Lim, SH Ton, KA Kadir - Lipids in Health and Disease, 2010 - Springer
Background The metabolic syndrome, known also as the insulin resistance syndrome, refers
to the clustering of several risk factors for atherosclerotic cardiovascular disease …

[HTML][HTML] Lipoprotein lipase expression, serum lipid and tissue lipid deposition in orally-administered glycyrrhizic acid-treated rats

WYA Lim, YY Chia, SY Liong, SH Ton, KA Kadir… - Lipids in Health and …, 2009 - Springer
Abstract Background The metabolic syndrome (MetS) is a cluster of metabolic abnormalities
comprising visceral obesity, dyslipidaemia and insulin resistance (IR). With the onset of IR …

Glycyrrhizic acid prevents high calorie diet− induced metabolic aberrations despite the suppression of peroxisome proliferator-activated receptor γ expression

HS Cheng, HP Yaw, SH Ton, SM Choy, JMXF Kong… - Nutrition, 2016 - Elsevier
Objective To investigate the effects of glycyrrhizic acid supplementation on glucose and lipid
metabolism in rodents consuming a high-fat, high-sucrose diet. Methods Twenty-four male, 8 …

[HTML][HTML] Glycyrrhizic acid can attenuate metabolic deviations caused by a high-sucrose diet without causing water retention in male Sprague-Dawley rats

HA Fernando, C Chandramouli, D Rosli, YL Lam… - Nutrients, 2014 - mdpi.com
Glycyrrhizic acid (GA) ameliorates many components of the metabolic syndrome, but its
potential therapeutic use is marred by edema caused by inhibition of renal 11β …

Effects of glycyrrhizic acid on 11 β-hydroxysteroid dehydrogenase (11 βHSD1 and 2) activities and HOMA-IR in rats at different treatment periods

YY Yin, SH Ton, KBA Kadir - Experimental and clinical …, 2010 - thieme-connect.com
Glycyrrhizic acid (GA) has been reported to inhibit postprandial blood glucose rise and 11 β-
hydroxysteroid dehydrogenase 1 (11 βHSD1) activity. As not much work has been done on …

Amelioration of glucose homeostasis by glycyrrhizic acid through gluconeogenesis rate-limiting enzymes

YY Chia, SY Liong, SH Ton… - European journal of …, 2012 - Elsevier
The activities of phosphoenolpyruvate carboxykinase (PEPCK) are influenced by active
glucocorticoids which are activated by 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) …

Effects of Glycyrrhizic Acid on Peroxisome Proliferator‐Activated Receptor Gamma (PPARγ), Lipoprotein Lipase (LPL), Serum Lipid and HOMA‐IR in Rats

C Yoke Yin, T So Ha, K Abdul Kadir - PPAR research, 2010 - Wiley Online Library
Studies on ligand binding potential of glycyrrhizic acid, a potential agonist to PPARγ,
displayed encouraging results in amelioration of metabolic syndrome. The regulation of …

[HTML][HTML] Modulation of lipid metabolism in glycyrrhizic acid-treated rats fed on a high-calorie diet and exposed to short or long-term stress

HP Yaw, SH Ton, HF Chin, MKA Karim… - … Journal of Physiology …, 2015 - ncbi.nlm.nih.gov
Stress and high-calorie diets increase the risk of developing metabolic syndrome.
Glycyrrhizic acid (GA) has been shown to improve dyslipidaemia in rats fed on a high-calorie …

Effects of glycyrrhetic acid (GE) on some gluconeogenic enzymes, lipoprotein lipase and peroxisome proliferator-activated receptors alpha and gamma

HP Yaw, SH Ton, KA Kadir, TY Tan… - The Open Bioactive …, 2013 - benthamopen.com
The aim of this study was to examine the role of glycyrrhetic acid (GE) as a potential
compound in the amelioration of metabolic syndrome. Rats given intraperitoneal injection of …