Clinicopathological indicators for TERT promoter mutation in papillary thyroid carcinoma

HY Na, HW Yu, W Kim, JH Moon, CH Ahn… - Clinical …, 2022 - Wiley Online Library
Objective Mutations in the telomerase reverse transcriptase (TERT) promoter have been
reported as a convincing prognostic factor in papillary thyroid carcinomas (PTCs). We aimed …

Prognostic Significance of TERT Promoter Mutations in Papillary Thyroid Carcinomas in a BRAFV600E Mutation–Prevalent Population

SE Lee, TS Hwang, YL Choi, HS Han, WS Kim… - Thyroid, 2016 - liebertpub.com
Background: The role of telomerase reverse transcriptase (TERT) promoter mutations in
differentiated thyroid cancer has been well established. These mutations have a significantly …

[PDF][PDF] Low prevalence of somatic TERT promoter mutations in classic papillary thyroid carcinoma

MJ Jeon, WG Kim, S Sim, S Lim… - Endocrinology and …, 2016 - synapse.koreamed.org
Background: Transcriptional activating mutations of telomerase reverse transcriptase (TERT)
are associated with more aggressive thyroid cancer. We evaluated the significance of TERT …

Prospective Analysis of TERT Promoter Mutations in Papillary Thyroid Carcinoma at a Single Institution

YS Choi, SW Choi, JW Yi - Journal of Clinical Medicine, 2021 - mdpi.com
Background: Papillary thyroid cancer (PTC) has the highest cancer incidence in Korea. It is
known that some thyroid cancers have aggressive clinical behavior and a poor prognosis …

TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas

A Tanaka, M Matsuse, V Saenko, T Nakao… - Thyroid, 2019 - liebertpub.com
Background: Telomerase reverse transcriptase (TERT) promoter mutations have been found
in a subset of papillary thyroid carcinomas (PTCs) and are associated with tumor …

TERT Promoter Mutations and Their Impact on Gene Expression Profile in Papillary Thyroid Carcinoma

D Rusinek, A Pfeifer, M Cieslicka, M Kowalska… - Cancers, 2020 - mdpi.com
Background: Telomerase reverse transcriptase promoter (TERT p) mutations are related to a
worse prognosis in various malignancies, including papillary thyroid carcinoma (PTC). Since …

Telomerase in differentiated thyroid cancer: promoter mutations, expression and localization

M Muzza, C Colombo, S Rossi, D Tosi, V Cirello… - Molecular and cellular …, 2015 - Elsevier
Abstract Telomerase-reverse-transcriptase (TERT) promoter mutations have been recently
described in tumors. In the present large series, TERT mutations were found in 12% of …

[HTML][HTML] BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients

L Jin, E Chen, S Dong, Y Cai, X Zhang, Y Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The role of telomerase reverse transcriptase (TERT) gene promoter mutations in the
aggressiveness of papillary thyroid cancer (PTC) remains to be further investigated. Here we …

[HTML][HTML] TERT promoter mutations and tumor persistence/recurrence in papillary thyroid cancer

JK Myung, BK Kwak, JA Lim… - Cancer research and …, 2016 - synapse.koreamed.org
Purpose A telomerase reverse transcriptase (TERT) promoter mutation was identified in
thyroid cancer. This TERT promoter mutation is thought to be a prognostic molecular marker …

Clinicopathological significance of TERT promoter mutation in papillary thyroid carcinomas: a systematic review and meta‐analysis

D Yin, K Yu, R Lu, X Li, J Xu, M Lei, H Li… - Clinical …, 2016 - Wiley Online Library
Background The prognostic value of the telomerase reverse transcriptase (TERT) promoter
mutation, resulting in poor clinical outcomes of papillary thyroid carcinoma (PTC), has been …