An adult formulation of a five-component acellular pertussis vaccine combined with diphtheria and tetanus toxoids is safe and immunogenic in adolescents and adults

SA Halperin, B Smith, M Russell, P Hasselback… - Vaccine, 2000 - Elsevier
Pertussis is increasingly being recognized as an important cause of cough illness in
adolescents and adults. To evaluate the safety and immunogenicity of an adult formulation …

A randomized trial of two acellular pertussis vaccines (dTpa and pa) and a licensed diphtheria-tetanus vaccine (Td) in adults

FM Turnbull, TC Heath, BB Jalaludin, MA Burgess… - Vaccine, 2000 - Elsevier
A single blinded randomized controlled trial to compare the reactogenicity and
immunogenicity of adult formulated dTpa and monovalent pa vaccines with a licensed Td …

Overview of the clinical development of a diphtheria-tetanus-acellular pertussis vaccine

H Bogaerts, C Capiau, P Hauser… - Journal of Infectious …, 1996 - academic.oup.com
A tricomponent acellular pertussis vaccine containing pertussis toxoid, filamentous
hemagglutinin, and pertactin combined with diphtheria and tetanus toxoids (DTPa) was …

Toward a controlled human infection model of pertussis

TJ Merkel - Clinical Infectious Diseases, 2020 - academic.oup.com
Pertussis is a highly contagious disease caused by Bordetella pertussis, spread by
respiratory droplets [1, 2]. B. pertussis is a strict human pathogen with no other known …

[HTML][HTML] Developing better paediatric vaccines: the case of pertussis vaccine

SA Halperin - BioDrugs, 1999 - Springer
After 2 decades of development, acellular pertussis vaccines are becoming more widely
available for use. Products that contain from 1 to 5 purified antigens of Bordetella pertussis …

Immunogenicity and safety of a tetanus toxoid, reduced diphtheria toxoid and three-component acellular pertussis vaccine in adults 19–64 years of age

M Blatter, LR Friedland, WM Weston, P Li, B Howe - Vaccine, 2009 - Elsevier
PURPOSE: This study was conducted to assess the immunogenicity and safety of a tetanus
toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine containing three …

New combined tetanus-diptheria-acellular pertussis vaccines for adults: primary care physician attitudes and preferences

MM Davis, K Kretsinger, AE Cowan, S Stokley… - Human …, 2007 - Taylor & Francis
Availability of combined tetanus-diphtheria-acellular pertussis (Tdap) vaccines for adults
offers a new pertussis prevention strategy for the US. Successful uptake of Tdap vaccine will …

A decennial booster dose of reduced antigen content diphtheria, tetanus, acellular pertussis vaccine (Boostrix™) is immunogenic and well tolerated in adults

R Booy, O Van Der Meeren, SP Ng, F Celzo… - Vaccine, 2010 - Elsevier
Reduced-antigen-content diphtheria–tetanus–acellular-pertussis (dTpa) vaccines are
predominantly recommended for once-in-a-lifetime use. A second dTpa (Boostrix™ …

[引用][C] The 5 component acellular pertussis vaccine combined with tetanus and diphtheria toxoids was efficacious in adolescents and adults.

M Datta - Evidence-based Medicine, 2006 - europepmc.org
An adolescent-adult formulation tetanus and diptheria toxoids adsorbed combined with
acellular pertussis vaccine has comparable immunogenicity but less reactogenicity in …

Reactogenicity and immunogenicity of reduced antigen content diphtheria–tetanus–acellular pertussis vaccine (dTpa) administered as a booster to 4–6 year-old …

P Kosuwon, B Warachit, Y Hutagalung, T Borkird… - Vaccine, 2003 - Elsevier
A trial to compare the reactogenicity and immunogenicity of a reduced antigen content
diphtheria–tetanus–acellular pertussis (dTpa) vaccine with diphtheria–tetanus–whole-cell …