In this study, we propose a method for quantification of average hydrogen peroxide
concentration within a living cell that is based on the use of genetically encoded H 2 O 2 …

Although its concentration is generally not known, glutathione peroxidase-1 (GPx-1) is a key
enzyme in the removal of hydrogen peroxide (H2O2) in biological systems. Extrapolating …

The catalase within normal, intact human erythrocytes was completely inactivated with
amino triazole. The rate of 14CO2 evolution, when the cells were subsequently incubated …

The ability of oxyhaemoglobin and methaemoglobin to generate hydroxyl radicals (OH.)
from H2O2 has been investigated using deoxyribose and phenylalanine as 'detector …

HO2•, usually termed either hydroperoxyl radical or perhydroxyl radical, is the protonated
form of superoxide; the protonation/deprotonation equilibrium exhibits a pKa of around 4.8 …

When cells are exposed to an external source of H2O2, the rapid enzymatic consumption of
H2O2 inside the cell provides the driving force for the formation of the gradient across the …

Acute hypoxemic respiratory failure (AHRF) can result from diverse lung insults. Toxic
oxygen metabolites have been implicated in this clinical condition and in animal models of …

The presence of hydrogen peroxide, at levels sometimes exceeding 100 μM, in human urine
samples was established by three different assay methods: 2-oxoglutarate decarboxylation …

Incubation of horse-heart oxymyoglobin or metmyoglobin with excess H2O2 causes
formation of myoglobin (IV), followed by haem degradation. At the time when haem …

Endothelial cells are both significant sources and targets of reactive oxygen species,
including O 2⋅−, H 2 O 2,⋅ OH,⋅ NO, and ONOO−, which play important roles in vascular …