Reactive oxygen species (ROS) were seen as destructive molecules, but recently, they have
been shown also to act as second messengers in varying intracellular signaling pathways …

The superoxide radical, Oi-, is formed in living organisms and has many deleterious effects [l-
3]. There is considerable evidence that systems generating Oi-can form the hydroxyl radical …

Extracellular H2O2 release and intracellular H2O2 production were determined in rat lung
alveolar macrophages, rat alveolar type II cells, and cultured bovine aortic endothelial cells …

MATERIALS AND METHODS Metmyoglobin. The metmyoglobin (MetMb) used in these
experiments was obtained from horses' hearts, the method of preparation following that of …

The contributions of catalase (H 2 O 2: H 2 O 2 oxidoreductase EC 1.11. 1.6) and glutathione
peroxidase (H 2 O 2: GSH oxidoreductase EC 1.11. 1.19) to the removal of H 2 O 2 from red …

Key Points In clinical practice, the level of arterial oxygenation can be measured either
directly by blood gas sampling to measure partial pressure (P aO2) and percentage …

The time required by the red blood cells (RBC) to release the O 2 needed by the tissues may
be rate-limiting undet conditions of reduced O 2 supply (DO 2). A time-dependent …

This book is based on the papers presented at the" Fourth International Congress on
Oxygen Radicals (4-ICOR)," held June 27-July 3, 1987, at the University of California, La …

The electronic structure of ground state oxygen, which is essential for the life of all aerobic
organisms, makes it potentially dangerous for those organisms. Atmospheric oxygen …

Molecular hydrogen (H 2) was believed to be inert and nonfunctional in mammalian cells.
We overturned this concept by demonstrating that H 2 reacts with highly reactive oxidants …