The molecular basis of frontotemporal dementia

M Neumann, M Tolnay, IRA Mackenzie - Expert reviews in molecular …, 2009 - cambridge.org
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. Familial FTD has been linked to mutations in several genes, including those encoding …

Advances in understanding the molecular basis of frontotemporal dementia

R Rademakers, M Neumann… - Nature Reviews Neurology, 2012 - nature.com
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. Until recently, the underlying cause was known in only a minority of cases that were …

Frontotemporal dementia: from molecular mechanisms to therapy

C Haass, M Neumann - Journal of Neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a heterogeneous clinical syndrome characterized by
frontotemporal lobar degeneration (FTLD). Neuropathologically, FTLD is characterized by …

Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review

H Seelaar, JD Rohrer, YAL Pijnenburg… - Journal of Neurology …, 2011 - jnnp.bmj.com
Frontotemporal dementia (FTD) is the second most common young-onset dementia and is
clinically characterised by progressive behavioural change, executive dysfunction and …

Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies

IRA Mackenzie, M Neumann - Journal of neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. The past decade has seen the discovery of several new FTD‐causing genetic …

Frontotemporal lobar degeneration: Pathogenesis, pathology and pathways to phenotype

DMA Mann, JS Snowden - Brain Pathology, 2017 - Wiley Online Library
Abstract Frontotemporal Lobar Degeneration (FTLD) is a clinically, pathologically and
genetically heterogeneous group of disorders that affect principally the frontal and temporal …

[HTML][HTML] The genetics and neuropathology of frontotemporal lobar degeneration

A Sieben, T Van Langenhove, S Engelborghs… - Acta …, 2012 - Springer
Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of disorders
characterized by disturbances of behavior and personality and different types of language …

Frontotemporal dementia: implications for understanding Alzheimer disease

M Goedert, B Ghetti… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Frontotemporal dementia (FTD) comprises a group of behavioral, language, and movement
disorders. On the basis of the nature of the characteristic protein inclusions, frontotemporal …

[HTML][HTML] Clinic, neuropathology and molecular genetics of frontotemporal dementia: a mini-review

X Pan, X Chen - Translational neurodegeneration, 2013 - Springer
Frontotemporal lobar degeneration (FTLD) represents a group of clinically,
neuropathologically and genetically heterogeneous disorders with plenty of overlaps …

The complex aetiology of frontotemporal lobar degeneration

SM Pickering-Brown - Experimental neurology, 2007 - Elsevier
Frontotemporal lobar degeneration (FTLD) is now a widely recognised form of dementia.
This heterogeneous disease has been of particular interest to geneticists due to its high rate …