Molecular genetics of polycystic ovary syndrome: an update

L Li, KH Baek - Current Molecular Medicine, 2015 - ingentaconnect.com
Polycystic ovary syndrome (PCOS) is a complex genetic disorder caused by interplay
between several 'susceptibility'genes and environment factors. In the past few years …

Genetics of polycystic ovary syndrome

TM Barber, S Franks - Polycystic ovary syndrome, 2013 - karger.com
Polycystic ovary syndrome (PCOS) is an oligogenic condition, with a heritability of∼ 70%.
PCOS is also associated with obesity, which itself is heavily influenced by genetic variants …

Genetic studies on polycystic ovary syndrome

H Zhao, Y Lv, L Li, ZJ Chen - Best practice & research Clinical obstetrics & …, 2016 - Elsevier
Highlights•This paper sorts out most of the polycystic ovary syndrome (PCOS)-related
candidate genes and highlights some of the key genes.•A review of the results of recent …

Polycystic ovarian syndrome: a complex disease with a genetics approach

H Nautiyal, SS Imam, S Alshehri, MM Ghoneim, M Afzal… - Biomedicines, 2022 - mdpi.com
Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder affecting females in
their reproductive age. The early diagnosis of PCOS is complicated and complex due to …

Genetic basis of polycystic ovary syndrome (PCOS): current perspectives

MJ Khan, A Ullah, S Basit - The application of clinical genetics, 2019 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant
proportion of the global population. It is the main cause of anovulatory infertility in women …

Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment

E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and is
associated with a substantially increased lifetime risk of comorbidities, including type 2 …

Genetics of polycystic ovary syndrome

K Mykhalchenko, D Lizneva, T Trofimova… - Expert review of …, 2017 - Taylor & Francis
Introduction: Polycystic ovary syndrome (PCOS) is a hormonal and metabolic disorder
affecting 5 to 20% of reproductive-aged women worldwide that results in androgen excess …

The role of genes in the polycystic ovary syndrome: predisposition and mechanisms

E Deligeoroglou, C Kouskouti… - Gynecological …, 2009 - Taylor & Francis
The polycystic ovary syndrome (PCOS), mainly characterized by clinical and/or biochemical
hyperandrogenism, ovarian dysfunction and/or polycystic morphology as well as associated …

Polycystic ovary syndrome: the epigenetics behind the disease

MC Eiras, DP Pinheiro, KAM Romcy, RA Ferriani… - Reproductive …, 2022 - Springer
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders,
affecting approximately 5–20% of women of reproductive age. PCOS is a multifactorial …

Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome

DA Dumesic, SE Oberfield, E Stener-Victorin… - Endocrine …, 2015 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a heterogeneous and complex disorder that has both
adverse reproductive and metabolic implications for affected women. However, there is …