[HTML][HTML] A BioID-derived proximity interactome for SARS-CoV-2 proteins

DG May, L Martin-Sancho, V Anschau, S Liu… - Viruses, 2022 - mdpi.com
The novel coronavirus SARS-CoV-2 is responsible for the ongoing COVID-19 pandemic and
has caused a major health and economic burden worldwide. Understanding how SARS …

Global BioID-based SARS-CoV-2 proteins proximal interactome unveils novel ties between viral polypeptides and host factors involved in multiple COVID19 …

EMN Laurent, Y Sofianatos, A Komarova, JP Gimeno… - BioRxiv, 2020 - biorxiv.org
The worldwide SARS-CoV-2 outbreak poses a serious challenge to human societies and
economies. SARS-CoV-2 proteins orchestrate complex pathogenic mechanisms that …

A SARS-CoV-2–host proximity interactome

P Samavarchi-Tehrani, H Abdouni, JDR Knight… - BioRxiv, 2020 - biorxiv.org
Viral replication is dependent on interactions between viral polypeptides and host proteins.
Identifying virus-host protein interactions can thus uncover unique opportunities for …

[HTML][HTML] An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity

Y Zhang, L Shang, J Zhang, Y Liu, C Jin, Y Zhao… - Cell Chemical …, 2022 - cell.com
The global epidemic caused by the coronavirus severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) has resulted in the infection of over 200 million people. To …

[HTML][HTML] A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Y Zhou, Y Liu, S Gupta, MI Paramo, Y Hou, C Mao… - Nature …, 2023 - nature.com
Studying viral–host protein–protein interactions can facilitate the discovery of therapies for
viral infection. We use high-throughput yeast two-hybrid experiments and mass spectrometry …

[HTML][HTML] Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

HH Hoffmann, FJ Sánchez-Rivera, WM Schneider… - Cell host & …, 2021 - cell.com
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
devastated the global economy and claimed more than 1.7 million lives, presenting an …

Comprehensive analysis of the host-virus interactome of SARS-CoV-2

Z Chen, C Wang, X Feng, L Nie, M Tang, H Zhang… - Biorxiv, 2021 - biorxiv.org
Host-virus protein-protein interaction is the key component of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) lifecycle. We conducted a comprehensive …

[HTML][HTML] Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

S Sadegh, J Matschinske, DB Blumenthal… - Nature …, 2020 - nature.com
Abstract Coronavirus Disease-2019 (COVID-19) is an infectious disease caused by the
SARS-CoV-2 virus. Various studies exist about the molecular mechanisms of viral infection …

[PDF][PDF] A SARS-CoV-2-human protein-protein interaction map reveals drug targets and potential drug-repurposing

MJ O'Meara, JZ Guo, DL Swaney, TA Tummino… - BioRxiv, 2020 - biorxiv.org
An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of COVID-19
respiratory disease, has infected over 290,000 people since the end of 2019, killed over …

Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis

J Li, M Guo, X Tian, C Liu, X Wang, X Yang, P Wu… - BioRxiv, 2020 - biorxiv.org
The ongoing coronavirus disease (COVID-19) pandemic caused by Severe Acute
Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a global public health concern due …