A primer on the clinical aspects of sarcoidosis for the basic and translational scientist

MA Judson - Journal of Clinical Medicine, 2021 - mdpi.com
The immunopathogenesis of sarcoidosis remains unclear. This failure in understanding has
been clinically impactful, as it has impeded the accurate diagnosis, treatment, and …

Sarcoidosis as an autoimmune disease

AA Starshinova, AM Malkova, NY Basantsova… - Frontiers in …, 2020 - frontiersin.org
Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis
still remain unknown. Most researchers allude to the possible autoimmune or immune …

[HTML][HTML] Etiology of sarcoidosis: does infection play a role?

S Saidha, ES Sotirchos, C Eckstein - The Yale journal of biology …, 2012 - ncbi.nlm.nih.gov
Sarcoidosis is a granulomatous inflammatory disorder of unclear etiology, which is known to
affect multiple organ systems including the lungs, heart, skin, central nervous system, and …

Advances in understanding the immunopathology of sarcoidosis and implications on therapy

F Cinetto, C Agostini - Expert review of clinical immunology, 2016 - Taylor & Francis
Introduction: Sarcoidosis is a multi-systemic granulomatous disease of unknown aetiology.
Ethnicity and environmental factors may influence disease incidence, phenotype and …

Sarcoidosis and autoimmunity: In the depth of a complex relationship

L Rizzi, C Sabbà, P Suppressa - Frontiers in Medicine, 2022 - frontiersin.org
Sarcoidosis is a chronic granulomatous disease that can virtually affect any organ. Its
etiology is unknown, although it has been proposed that environmental or biological agents …

Etiology of sarcoidosis

ES Chen, DR Moller - Clinics in chest medicine, 2008 - Elsevier
Research over the past decade has advanced our understanding of the pathogenesis of
sarcoidosis and provided new insights into potential causes of this disease. It is important to …

Sarcoidosis: Evolving Concepts

JC Grutters - Seminars in Respiratory and Critical Care …, 2017 - thieme-connect.com
Despite a history of more than 100 years and a huge amount of scientific effort sarcoidosis
still remains an enigmatic disorder of unknown etiology. The disease challenges many …

Etiology and immunopathogenesis of sarcoidosis: novel insights

E Beijer, M Veltkamp, B Meek… - Seminars in Respiratory …, 2017 - thieme-connect.com
Sarcoidosis is a disorder of unknown etiology. It is a systemic disease, frequently involving
the lungs, skin, eyes, and lymph nodes. It is characterized by formation of noncaseating …

Clinical presentations, pathogenesis, and therapy of sarcoidosis: state of the art

F Polverino, E Balestro, P Spagnolo - Journal of clinical medicine, 2020 - mdpi.com
Sarcoidosis is a systemic disease of unknown etiology characterized by the presence of
noncaseating granulomas that can occur in any organ, most commonly the lungs. Early and …

The immunology of sarcoidosis

AK Gerke, G Hunninghake - Clinics in chest medicine, 2008 - Elsevier
Sarcoidosis continues to be a disease of research interest because of its complicated
immune mechanisms and elusive etiology. So far, it has been established that …