[HTML][HTML] Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease

NT Ventham, NA Kennedy, AT Adams, R Kalla… - Nature …, 2016 - nature.com
Epigenetic alterations may provide important insights into gene-environment interaction in
inflammatory bowel disease (IBD). Here we observe epigenome-wide DNA methylation …

Microbiota regulate intestinal epithelial gene expression by suppressing the transcription factor Hepatocyte nuclear factor 4 alpha

JM Davison, CR Lickwar, L Song, G Breton… - Genome …, 2017 - genome.cshlp.org
Microbiota influence diverse aspects of intestinal physiology and disease in part by
controlling tissue-specific transcription of host genes. However, host genomic mechanisms …

[HTML][HTML] Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration

H Abo, B Chassaing, A Harusato, M Quiros… - Nature …, 2020 - nature.com
Gut microbiota and their metabolites are instrumental in regulating intestinal homeostasis.
However, early-life microbiota associated influences on intestinal development remain …

Impact of dietary gut microbial metabolites on the epigenome

C Gerhauser - … Transactions of the Royal Society B …, 2018 - royalsocietypublishing.org
Within the past decade, epigenetic mechanisms and their modulation by natural products
have gained increasing interest. Dietary bioactive compounds from various sources …

[HTML][HTML] Gut microbiota as important mediator between diet and DNA methylation and histone modifications in the host

P D'Aquila, L Lynn Carelli, F De Rango, G Passarino… - Nutrients, 2020 - mdpi.com
The human gut microbiota is a complex ecosystem consisting of trillions of microorganisms
that inhabit symbiotically on and in the human intestine. They carry out, through the …

[HTML][HTML] Dynamic of the human gut microbiome under infectious diarrhea

HC The, SNH Le - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Infectious diarrhea disrupts the gut microbiome and reduce its diversity.•
Enterobacteriaceae, Streptococcus and oral bacteria bloom in gut following diarrhea.•Mucin …

Metagenomics: key to human gut microbiota

S Maccaferri, E Biagi, P Brigidi - Digestive diseases, 2011 - karger.com
The human gastrointestinal tract harbors the most complex human microbial ecosystem
(intestinal microbiota). The comprehensive genome of these microbial populations …

Comparative metagenomics and population dynamics of the gut microbiota in mother and infant

PA Vaishampayan, JV Kuehl, JL Froula… - Genome biology and …, 2010 - academic.oup.com
Colonization of the gastrointestinal tract (GIT) of human infants with a suitable microbial
community is essential for numerous aspects of health, but the progression of events by …

[HTML][HTML] Deterministic transition of enterotypes shapes the infant gut microbiome at an early age

L Xiao, J Wang, J Zheng, X Li, F Zhao - Genome biology, 2021 - Springer
Background The succession of the gut microbiota during the first few years plays a vital role
in human development. We elucidate the characteristics and alternations of the infant gut …

Studying vertical microbiome transmission from mothers to infants by strain-level metagenomic profiling

F Asnicar, S Manara, M Zolfo, DT Truong, M Scholz… - …, 2017 - Am Soc Microbiol
The gut microbiome becomes shaped in the first days of life and continues to increase its
diversity during the first months. Links between the configuration of the infant gut microbiome …