Purpose The aim of this study was to investigate the longitudinal positron emission
tomography (PET) metabolic changes in the elderly. Procedures Nineteen nondemented …

In pathologic brains with morphological alterations, the process of spatial normalization, as
performed by SPM methods, may introduce a confounding effect in the measurement of …

To improvethe diagnosticperformanceof PET as an aid in
evaluatingpatientssuspectedofhawig@ 4Jzhalmer'sdisease, we devalopeda …

Quantification approaches of positron emission tomography (PET) imaging provide user-
independent evaluation of pathophysiological processes in living brains, which have been …

Diagnostic accuracy in FDG-PET imaging highly depends on the operating procedures. In
this clinical study on dementia, we compared the diagnostic accuracy at a single-subject …

Dynamic positron emission tomography (PET) data are usually quantified using
compartment models (CMs) or derived graphical approaches. Often, however, CMs either do …

18F-DMFP-PET is an emerging neuroimaging modality used to diagnose Parkinson's
disease (PD) that allows us to examine postsynaptic dopamine D 2/3 receptors. Like other …

The aging process is thought to result in changes in synaptic activity reflecting both
functional and structural cell derangement. However, previous PET reports on age-related …

This article investigates longitudinal imaging characteristics of early cognitive decline during
normal aging, leveraging on high-dimensional imaging pattern classification methods for the …

Age and gender are the important factors for brain metabolic declines in both normal aging
and neurodegeneration, and the confounding effects may influence early and differential …