The study of N-linked glycans is among the most challenging bioanalytical tasks because of
their complexity and variety. The presence of glycoform families that differ only in branching …

2-Aminoacridone (2-AMAC) has been used to derivatize mixtures of N-linked
oligosaccharides released from α1-acid glycoprotein and immunoglobulin G. In each case …

Abstract Characterization of glycans present on glycoproteins has become of increasing
importance due to their biological implications, such as protein folding, immunogenicity, cell …

An ideal method for the analysis of N-glycans would both identify the isomeric structure and
deliver a true picture of the relative, if not absolute, amounts of the various structures in one …

Complex carbohydrates are ubiquitous in nature and represent one of the major classes of
biopolymers. They can exhibit highly diverse structures with multiple branched sites as well …

Negative ion electrospray (ESI) fragmentation spectra derived from anion-adducted glycans
were evaluated for structural determination of N-linked glycans and found to be among the …

Abstract We implemented 8‐aminopyrene‐1, 3, 6‐trisulfonic acid (APTS)‐labeled
asparagine‐linked glycan (N‐glycan) profiling on a microfluidic electrophoresis platform …

Glycosylation is an important post-translational modification of proteins present in the vast
majority of human proteins. For this reason, they are potentially new sources of biomarkers …

A simple and rapid “one-pot” methylation method to esterify sialic acids and construct a
permanent charge was developed for N-linked glycan analysis, which combined complete …

Glycosylation is one of the most common protein modifications and profoundly regulates
many biological processes. Aberrant glycosylation is reported to associate with diseases …