[HTML][HTML] TLR2/4 signaling pathway mediates sperm-induced inflammation in bovine endometrial epithelial cells in vitro
We have recently shown that sperm attachment to bovine endometrial epithelial cells
(BEECs) triggers uterine local innate immunity with induction of a pro-inflammatory response …
(BEECs) triggers uterine local innate immunity with induction of a pro-inflammatory response …
[HTML][HTML] Sperm activate TLR2/TLR1 heterodimerization to induce a weak proinflammatory response in the bovine uterus
Toll-like receptor 2 (TLR2) signaling pathway is involved in the sperm-triggered uterine
inflammatory response at insemination, but its precise mechanism at molecular-level …
inflammatory response at insemination, but its precise mechanism at molecular-level …
A proinflammatory response of bovine endometrial epithelial cells to active sperm in vitro
AE Elweza, MA Ezz, TJ Acosta… - Molecular …, 2018 - Wiley Online Library
In the cow, cryopreserved semen is inseminated into the uterus, and most of sperm are
removed by backflow and phagocytes. Nevertheless, the mechanism responsible for sperm …
removed by backflow and phagocytes. Nevertheless, the mechanism responsible for sperm …
[HTML][HTML] Sperm Binding to Oviduct Epithelial Cells Enhances TGFB1 and IL10 Expressions in Epithelial Cells as Well as Neutrophils In Vitro: Prostaglandin E2 As a …
Sperm are allogenic to the female genital tract; however, oviducts provide optimal conditions
for survival and capacitation of these non-self cells until fertilization. Recently, we showed …
for survival and capacitation of these non-self cells until fertilization. Recently, we showed …
Sperm enter glands of preovulatory bovine endometrial explants and initiate inflammation
I Akthar, SS Suarez, VA Morillo, M Sasaki… - …, 2020 - rep.bioscientifica.com
We previously reported that sperm binding to cultured monolayers of bovine uterine
epithelial cells induces an acute inflammatory response involving the Toll-like receptor …
epithelial cells induces an acute inflammatory response involving the Toll-like receptor …
[HTML][HTML] Sperm interaction with the uterine innate immune system: toll-like receptor 2 (TLR2) is a main sensor in cattle
During the passage through the female reproductive tract, sperm interact with various
compartments and their immune systems. The immune system that protects the female …
compartments and their immune systems. The immune system that protects the female …
Seminal plasma modulates expression of endometrial inflammatory meditators in the bovine
Seminal plasma has conventionally been viewed as a transport and survival medium for
mammalian sperm; however, its role now extends beyond this process to actively targeting …
mammalian sperm; however, its role now extends beyond this process to actively targeting …
Toll-like receptor 4 and MYD88-dependent signaling mechanisms of the innate immune system are essential for the response to lipopolysaccharide by epithelial and …
Infection of the bovine endometrium with Gram-negative bacteria commonly causes uterine
disease. Toll-like receptor 4 (TLR4) on cells of the immune system bind Gram-negative …
disease. Toll-like receptor 4 (TLR4) on cells of the immune system bind Gram-negative …
TLR4 signaling is a major mediator of the female tract response to seminal fluid in mice
Seminal fluid interacts with epithelial cells lining the female reproductive tract to induce
expression of proinflammatory cytokines and chemokines, initiating immune tolerance …
expression of proinflammatory cytokines and chemokines, initiating immune tolerance …
Regulation of innate immune function in bovine oviduct epithelial cells in culture: the homeostatic role of epithelial cells in balancing Th1/Th2 response
This study aimed to investigate the role of epithelial cells in regulating innate immunity in
bovine oviduct epithelial cell (BOEC) culture. We studied the effect of Escherichia coli …
bovine oviduct epithelial cell (BOEC) culture. We studied the effect of Escherichia coli …