Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus
JM Miano, X Long, K Fujiwara - American Journal of …, 2007 - journals.physiology.org
Serum response factor (SRF) is a highly conserved and widely expressed, single copy
transcription factor that theoretically binds up to 1,216 permutations of a 10-base pair cis …
transcription factor that theoretically binds up to 1,216 permutations of a 10-base pair cis …
Organization and myogenic restricted expression of the murine serum response factor gene: a role for autoregulation
NS Belaguli, LA Schildmeyer, RJ Schwartz - Journal of Biological Chemistry, 1997 - ASBMB
Serum response factor (SRF), a member of an ancient family of DNA-binding proteins, is
generally assumed to be a ubiquitous transcription factor involved in regulating growth factor …
generally assumed to be a ubiquitous transcription factor involved in regulating growth factor …
Restricted inactivation of serum response factor to the cardiovascular system
Serum response factor (SRF) directs programs of gene expression linked to growth and
muscle differentiation. To investigate the role of SRF in cardiovascular development, we …
muscle differentiation. To investigate the role of SRF in cardiovascular development, we …
Serum response factor: toggling between disparate programs of gene expression
JM Miano - Journal of molecular and cellular cardiology, 2003 - Elsevier
Serum response factor (SRF) is a widely expressed transcription factor involved in
orchestrating disparate programs of gene expression linked to muscle differentiation and …
orchestrating disparate programs of gene expression linked to muscle differentiation and …
Signal-regulated activation of serum response factor is mediated by changes in actin dynamics
A Sotiropoulos, D Gineitis, J Copeland, R Treisman - Cell, 1999 - cell.com
Serum response factor (SRF) regulates transcription of many serum-inducible and muscle-
specific genes. Using a functional screen, we identified LIM kinase-1 as a potent activator of …
specific genes. Using a functional screen, we identified LIM kinase-1 as a potent activator of …
[HTML][HTML] Role of serum response factor in the pathogenesis of disease
JM Miano - Laboratory investigation, 2010 - Elsevier
Serum response factor (SRF) is a ubiquitously expressed transcription factor that binds to a
DNA cis element known as the CArG box, which is found in the proximal regulatory regions …
DNA cis element known as the CArG box, which is found in the proximal regulatory regions …
Actin'together: serum response factor, its cofactors and the link to signal transduction
G Posern, R Treisman - Trends in cell biology, 2006 - cell.com
The vast diversity of cellular types and behaviours is mainly the result of combinatorial
interactions between a limited number of transcription factors and cellular signalling …
interactions between a limited number of transcription factors and cellular signalling …
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice
S Li, MP Czubryt, J McAnally… - Proceedings of the …, 2005 - National Acad Sciences
Serum response factor (SRF) controls the transcription of muscle genes by recruiting a
variety of partner proteins, including members of the myocardin family of transcriptional …
variety of partner proteins, including members of the myocardin family of transcriptional …
Dominant negative murine serum response factor: alternative splicing within the activation domain inhibits transactivation of serum response factor binding targets
NS Belaguli, W Zhou, THT Trinh… - … and cellular biology, 1999 - Am Soc Microbiol
Primary transcripts encoding the MADS box superfamily of proteins, such as MEF2 in
animals and ZEMa in plants, are alternatively spliced, producing several isoformic species …
animals and ZEMa in plants, are alternatively spliced, producing several isoformic species …
Differential usage of signal transduction pathways defines two types of serum response factor target gene
D Gineitis, R Treisman - Journal of Biological Chemistry, 2001 - ASBMB
Activation of the transcription factor serum response factor (SRF) is dependent on Rho-
controlled changes in actin dynamics. We used pathway-specific inhibitors to compare the …
controlled changes in actin dynamics. We used pathway-specific inhibitors to compare the …