CGRP in human models of migraine

H Ashina, HW Schytz, M Ashina - Calcitonin Gene-Related Peptide …, 2019 - Springer
Over the past three decades, calcitonin gene-related peptide (CGRP) has emerged as a key
molecule. Provocation experiments have demonstrated that intravenous CGRP infusion …

Calcitonin gene-related peptide and migraine

N Karsan, PJ Goadsby - Current opinion in neurology, 2015 - journals.lww.com
This article highlights the evidence behind the role of CGRP in migraine and the state of
CGRP-based mechanism treatment development. We present a summary of the evidence …

Calcitonin gene‐related peptide (CGRP) and migraine

PL Durham - Headache: The Journal of Head and Face Pain, 2006 - Wiley Online Library
The neuropeptide calcitonin gene‐related peptide (CGRP) has long been postulated to play
an integral role in the pathophysiology of migraine. While clinical findings are consistent with …

CGRP in animal models of migraine

AS Wattiez, M Wang, AF Russo - Calcitonin Gene-Related Peptide (CGRP …, 2019 - Springer
With the approval of calcitonin gene-related peptide (CGRP) and CGRP receptor
monoclonal antibodies by the Federal Drug Administration, a new era in the treatment of …

Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation

AC Raddant, AF Russo - Expert reviews in molecular medicine, 2011 - cambridge.org
Over the past two decades, a convergence of basic and clinical evidence has established
the neuropeptide calcitonin-gene-related peptide (CGRP) as a key player in migraine …

Calcitonin gene-related peptide (CGRP): a new target for migraine

AF Russo - Annual review of pharmacology and toxicology, 2015 - annualreviews.org
Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …

Inhibition of calcitonin gene‐related peptide function: a promising strategy for treating migraine

PL Durham - Headache: The Journal of Head and Face Pain, 2008 - Wiley Online Library
The neuropeptide calcitonin gene‐related peptide (CGRP) is implicated in the underlying
pathology of migraine. Serum levels of CGRP, which are elevated during a migraine attack …

Calcitonin gene‐related peptide (CGRP) and migraine current understanding and state of development

ME Bigal, S Walter, AM Rapoport - Headache: The Journal of …, 2013 - Wiley Online Library
Calcitonin gene‐related peptide (CGRP) is a ubiquitous neuropeptide found at the very
centers of the migraine process, both centrally and peripherally. It has been under careful …

Calcitonin gene-related peptide (CGRP): role in migraine pathophysiology and therapeutic targeting

AS Wattiez, LP Sowers, AF Russo - Expert opinion on therapeutic …, 2020 - Taylor & Francis
Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a
critical player in migraine pathophysiology. Excitement has grown regarding CGRP because …

[HTML][HTML] Calcitonin gene-related peptide causes migraine aura

HM Al-Khazali, H Ashina, A Wiggers, K Rose… - The Journal of …, 2023 - Springer
Background Although the involvement of calcitonin gene-related peptide (CGRP) in
migraines is well-established, its specific role in investigating the aura phase, which often …