When withdrawal symptoms change the meaning of research data

F Cosci, VA Chouinard, G Chouinard - Psychotherapy and …, 2022 - karger.com
The ANTLER trial [1] assessed the effects of fixed-dose antidepressant maintenance
compared to discontinuation in primary care patients who felt well enough to consider …

Clinical utility of semistructured interview and scales to assess withdrawal syndromes with dose reduction or discontinuation of selective serotonin reuptake inhibitors …

F Cosci, S Romanazzo, G Mansueto… - Journal of Clinical …, 2022 - journals.lww.com
Background Withdrawal syndromes can occur after dose reduction or discontinuation of
selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake …

Physicians' knowledge of antidepressant withdrawal effects: a survey

AH Young, A Currie - Journal of Clinical Psychiatry, 1997 - psychiatrist.com
METHOD We designed a questionnaire (Appendix 1) to elicit information on physicians'
awareness of and experience with antidepressant discontinuation events. The 2-page …

The long and winding road of discontinuing long‐term use of antidepressants: Learning from my experience

C Wilson - Journal of Psychiatric and Mental Health Nursing, 2020 - Wiley Online Library
Accessible Summary What is known on the subject? More people experience withdrawal
symptoms when weaning off antidepressants than previously thought; particularly after …

Are antidepressants a double-edged sword? Treatment emergent affective switch or antidepressant discontinuation syndrome.

N Agalawatta, C Kaufmann, Y Byrow… - Australian & New …, 2017 - search.ebscohost.com
Are antidepressants a double-edged sword? Treatment emergent affective switch or
antidepressant discontinuation syndrome Neelya Page 1 ANZJP Correspondence 405 …

Comparative effects of 15 antidepressants on the risk of withdrawal syndrome: a real-world study using the WHO pharmacovigilance database

JB Quilichini, A Revet, P Garcia, R Bouquié… - Journal of Affective …, 2022 - Elsevier
Background While case reports and clinical trials reported withdrawal syndrome after
reduction and/or discontinuation of antidepressant drugs, no large study has been …

Discontinuing antidepressant drugs: lesson from a failed trial and extensive clinical experience

GA Fava, C Belaise - Psychotherapy and Psychosomatics, 2018 - karger.com
Scholten et al.[1] reported on the first randomized controlled trial that attempted to prevent
relapse in patients with remitted anxiety disorder who discontinued antidepressant drugs …

Antidepressant Discontinuation Syndrome in Clinical Practice

V Verbenko - European Psychiatry, 2015 - cambridge.org
Antidepressant Discontinuation Syndrome–(995.29 in DSM-5, 2013) particularly if treatment
is stopped suddenly, is common, but modern times they have no common evidence …

A survey of UK general practitioners about depression, antidepressants and withdrawal: implementing the 2019 Public Health England report

J Read, J Renton, C Harrop… - Therapeutic …, 2020 - journals.sagepub.com
Background: In 2019, a literature review indicated that more than half of people who try to
come off antidepressants experience withdrawal effects. Both the National Institute of Health …

Early relapse after antidepressant discontinuation may represent antidepressant discontinuation syndrome in major depressive disorder: A meta-analysis.

T Kishi, K Sakuma, M Hatano, M Okuya, N Iwata - 2023 - psycnet.apa.org
The authors hypothesized that early relapse (eg, within 2–3 weeks or 1 month after
antidepressant discontinuation) in placebo recipients might represent antidepressant …