The effect of rate of antidepressant tapering on the incidence of discontinuation symptoms: a randomised study

A Tint, PM Haddad… - Journal of …, 2008 - journals.sagepub.com
Twenty eight patients treated with selective serotonin reuptake inhibitors/venlafaxine were
randomized to a three-day (short) or 14-day (longer) anti—depressant taper and openly …

[HTML][HTML] Discontinuation of antidepressant medications: a significant healthcare problem insufficiently addressed by the NICE guidelines

F Cosci, VA Chouinard, G Chouinard - Psychotherapy and …, 2023 - karger.com
In 2008, Chouinard and Chouinard [1] published an editorial in Psychotherapy and
Psychosomatics applying the basic pharmacological concepts of withdrawal to symptoms …

Antidepressants: Course and Duration of Therapy, Withdrawal Syndromes, and Resistance to Therapy

L Brandt, A Heinz, J Henssler - NeuroPsychopharmacotherapy, 2022 - Springer
The course and duration of therapy, withdrawal syndromes, and resistance to therapy are
important clinical topics in antidepressant therapy. The reviewed clinical evidence may help …

Antidepressant discontinuation: a review of the literature

M Lejoyeux, J Adès - Journal of Clinical Psychiatry, 1997 - psychiatrist.com
Sudden or tapered withdrawal from treatment with antidepressants, including monoamine
oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), and serotonin selective …

Predicting relapse after antidepressant withdrawal–a systematic review

IM Berwian, H Walter, E Seifritz, QJM Huys - Psychological medicine, 2017 - cambridge.org
A substantial proportion of the burden of depression arises from its recurrent nature. The risk
of relapse after antidepressant medication (ADM) discontinuation is high but not uniform …

Antidepressant withdrawal syndrome: recognition, prevention and management

M Lejoyeux, J Adès, S Mourad, J Solomon, S Dilsaver - CNS drugs, 1996 - Springer
Withdrawal from tricyclic antidepressants (TCAs), monoamine oxidase inhibitors (MAOIs)
and selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs) can …

[HTML][HTML] Discontinuing antidepressants: how can clinicians guide patients and drive research?

MK Jha - The Journal of Clinical Psychiatry, 2019 - psychiatrist.com
Recent media reports have refocused attention on the syndromic manifestation experienced
by some patients as they discontinue their antidepressant medication (“discontinuation …

[HTML][HTML] The need for antidepressant withdrawal support services: recommendations from 708 patients

J Read, S Lewis, M Horowitz, J Moncrieff - Psychiatry Research, 2023 - Elsevier
Approximately half of the tens of millions of people currently taking antidepressants will
experience withdrawal symptoms when they try to reduce or come off them. Nearly half of …

New insights on the antidepressant discontinuation syndrome

BH Harvey, FN Slabbert - … Psychopharmacology: Clinical and …, 2014 - Wiley Online Library
Objective Antidepressants are at best 50–55% effective. Non‐compliance and the
antidepressant discontinuation syndrome (ADS) are causally related yet poorly appreciated …

Discontinuation symptoms in depression and anxiety disorders

DS Baldwin, SA Montgomery, R Nil… - International Journal of …, 2007 - academic.oup.com
The present overview investigates whether different antidepressants have differing
discontinuation symptoms upon treatment cessation, if these symptoms vary between …