Factors affecting the transition of acute kidney injury to chronic kidney disease: Potential mechanisms and future perspectives

J Ogbadu, G Singh, D Aggarwal - European Journal of Pharmacology, 2019 - Elsevier
Acute kidney injury (AKI) is defined as a rapid loss of kidney function characterised by
inflammation and cell death, ultimately leading to further functional and structural renal …

[HTML][HTML] From Acute to Chronic: Unraveling the Pathophysiological Mechanisms of the Progression from Acute Kidney Injury to Acute Kidney Disease to Chronic …

TH Yeh, KC Tu, HY Wang, JY Chen - International journal of molecular …, 2024 - mdpi.com
This article provides a thorough overview of the biomarkers, pathophysiology, and molecular
pathways involved in the transition from acute kidney injury (AKI) and acute kidney disease …

Recent advances in acute kidney injury and its consequences and impact on chronic kidney disease

A Zuk, JV Bonventre - Current opinion in nephrology and …, 2019 - journals.lww.com
Recent advances in acute kidney injury and its consequences... : Current Opinion in
Nephrology and Hypertension Recent advances in acute kidney injury and its …

[HTML][HTML] Acute kidney injury

A Zuk, JV Bonventre - Annual review of medicine, 2016 - annualreviews.org
Acute kidney injury (AKI) is a global public health concern associated with high morbidity,
mortality, and healthcare costs. Other than dialysis, no therapeutic interventions reliably …

[HTML][HTML] From AKI to CKD: maladaptive repair and the underlying mechanisms

Z Wang, C Zhang - International journal of molecular sciences, 2022 - mdpi.com
Acute kidney injury (AKI) is defined as a pathological condition in which the glomerular
filtration rate decreases rapidly over a short period of time, resulting in changes in the …

Identifying common molecular mechanisms in experimental and human acute kidney injury

LMS Gerhardt, AP McMahon - Seminars in nephrology, 2022 - Elsevier
Acute kidney injury (AKI) is a highly prevalent, heterogeneous syndrome, associated with
increased short-and long-term mortality. A multitude of different factors cause AKI including …

[HTML][HTML] Therapies targeting epigenetic alterations in acute kidney injury-to-chronic kidney disease transition

F Tanemoto, I Mimura - Pharmaceuticals, 2022 - mdpi.com
Acute kidney injury (AKI) was previously thought to be a merely transient event; however,
recent epidemiological evidence supports the existence of a causal relationship between …

[HTML][HTML] Kidney inflammation, injury and regeneration

PC Baer, B Koch, H Geiger - International Journal of Molecular Sciences, 2020 - mdpi.com
Damage to kidney cells can occur due to a variety of ischemic and toxic insults and leads to
inflammation and cell death, which can result in acute kidney injury (AKI). Inflammation plays …

Comparison of acute kidney injury of different etiology reveals in-common mechanisms of tissue damage

M Hultström, M Becirovic-Agic… - Physiological …, 2018 - journals.physiology.org
Acute kidney injury (AKI) is a syndrome of reduced glomerular filtration rate and urine
production caused by a number of different diseases. It is associated with renal tissue …

Acute kidney injury to chronic kidney disease transition: insufficient cellular stress response

SA Strausser, D Nakano, T Souma - Current opinion in …, 2018 - journals.lww.com
Insufficient cellular stress adaptation may underpin the persistent activation of inflammatory
and fibrogenic signaling in damaged kidneys. We propose that harnessing cellular stress …