Background Higher nigral iron has been reported in Parkinson's disease (PD). Objective
The aim is to understand the dynamics of nigral iron accumulation in PD and its association …

Background Parkinson's disease (PD) is characterized in part by the progressive
accumulation of iron within the substantia nigra (SN); however, its spatial and temporal …

A growing body of evidence suggests nigral iron accumulation plays an important role in the
pathophysiology of Parkinson's disease (PD), contributing to dopaminergic neuron loss in …

Background and purpose: To investigate whether brain iron deposition correlates with motor
phenotypic expressions of Parkinson's disease. Methods: We subtyped patients with …

Background Previous studies investigating nigral iron accumulation used T2 or T2*‐
weighted contrasts to define the regions of interest (ROIs) in the substantia nigra with mixed …

Background and purpose To determine whether iron deposition in deep brain nuclei
assessed using high‐pass filtered phase imaging plays a role in motor disease severity in …

Purpose Because the roles of striatal‐thalamo‐cortical and cerebello‐thalamo‐cortical
circuits in the heterogeneous motor impairments of Parkinson's disease (PD) are becoming …

The identification of sensitive and specific biomarkers for Parkinson's disease (PD) poses an
important clinical challenge. A potential biomarker for early diagnosis and disease …

Background. Iron is considered to lead to neurodegeneration and has been hypothesized as
a possible cause of Parkinson's disease (PD). Susceptibility‐weighted imaging (SWI) is a …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor deficits
accompanying degeneration of substantia nigra pars compactor (SNc) neurons. Although …