Modification of proteins by metabolites in immunity
C Diskin, TAJ Ryan, LAJ O'neill - Immunity, 2021 - cell.com
Immunometabolism has emerged as a key focus for immunologists, with metabolic change
in immune cells becoming as important a determinant for specific immune effector …
in immune cells becoming as important a determinant for specific immune effector …
A guide to immunometabolism for immunologists
LAJ O'Neill, RJ Kishton, J Rathmell - Nature reviews immunology, 2016 - nature.com
In recent years a substantial number of findings have been made in the area of
immunometabolism, by which we mean the changes in intracellular metabolic pathways in …
immunometabolism, by which we mean the changes in intracellular metabolic pathways in …
Immunometabolism: an overview and therapeutic prospects in autoimmune diseases
C Stathopoulou, D Nikoleri, G Bertsias - Immunotherapy, 2019 - Taylor & Francis
Metabolism is a critical immune regulator under physiologic and pathologic conditions.
Culminating evidence has disentangled the contribution of distinct metabolic pathways …
Culminating evidence has disentangled the contribution of distinct metabolic pathways …
Driving immunity: all roads lead to metabolism
EJ Pearce, EL Pearce - Nature Reviews Immunology, 2018 - nature.com
In 2017, studies of cellular metabolism broadly permeated immunological research.
Accumulating data support the view that understanding how metabolism regulates immune …
Accumulating data support the view that understanding how metabolism regulates immune …
Metabolic modulation in macrophage effector function
C Diskin, EM Pålsson-McDermott - Frontiers in immunology, 2018 - frontiersin.org
Traditionally cellular respiration or metabolism has been viewed as catabolic and anabolic
pathways generating energy and biosynthetic precursors required for growth and general …
pathways generating energy and biosynthetic precursors required for growth and general …
Metabolic regulation of immune responses
K Ganeshan, A Chawla - Annual review of immunology, 2014 - annualreviews.org
The immune system defends against pathogens and maintains tissue homeostasis for the
life of the organism. These diverse functions are bioenergetically expensive, requiring …
life of the organism. These diverse functions are bioenergetically expensive, requiring …
Targeting immunometabolism as an anti-inflammatory strategy
EM Pålsson-McDermott, LAJ O'Neill - Cell research, 2020 - nature.com
The growing field of immunometabolism has taught us how metabolic cellular reactions and
processes not only provide a means to generate ATP and biosynthetic precursors, but are …
processes not only provide a means to generate ATP and biosynthetic precursors, but are …
Metabolic stress in the immune function of T cells, macrophages and dendritic cells
C Domblides, L Lartigue, B Faustin - Cells, 2018 - mdpi.com
Innate and adaptive immune cells from myeloid and lymphoid lineages resolve host
infection or cell stress by mounting an appropriate and durable immune response. Upon …
infection or cell stress by mounting an appropriate and durable immune response. Upon …
Immunometabolism: cellular metabolism turns immune regulator
Immune cells are highly dynamic in terms of their growth, proliferation, and effector functions
as they respond to immunological challenges. Different immune cells can adopt distinct …
as they respond to immunological challenges. Different immune cells can adopt distinct …
Unraveling the complex interplay between T cell metabolism and function
RI Klein Geltink, RL Kyle… - Annual review of …, 2018 - annualreviews.org
Metabolism drives function, on both an organismal and a cellular level. In T cell biology,
metabolic remodeling is intrinsically linked to cellular development, activation, function …
metabolic remodeling is intrinsically linked to cellular development, activation, function …