Synthesis, structure–activity relationship studies using density functional theory and in silico molecular docking on substituted benzohydrazide derivatives
The present study demonstrates the utility of benzohydrazide derivatives based on an
approach to identify potential targets for a series of synthesized compounds that show potent …
approach to identify potential targets for a series of synthesized compounds that show potent …
New2-((2-(2,4-dinitrophenyl)hydrazineeylidene) derivatives: design, synthesis, in silico, and in vitro anticancer studies
A series of novel hydrazone compounds have been synthesized by the condensation of
hydrazines and different substituted salicylaldehydes at a molar ratio of 1: 1 in one step …
hydrazines and different substituted salicylaldehydes at a molar ratio of 1: 1 in one step …
Synthesis, investigation of the crystal structure, DFT calculations, and in silico medicinal potential of hydrazono-and aminomethylene substituted pyrazolidine-3, 5 …
Y El Bakri, SA Siddique, SK Mohamed… - New Journal of …, 2024 - pubs.rsc.org
Two new pyrazolidine-3, 5-dione derivatives namely (Z)-4-(2-(4-bromophenyl) hydrazono)-1-
phenylpyrazolidine-3, 5-dione (2) and (E)-1-phenyl-4-((pyridin-2-ylamino) methylene) …
phenylpyrazolidine-3, 5-dione (2) and (E)-1-phenyl-4-((pyridin-2-ylamino) methylene) …
Synthesis, In Vitro Anticancer Activity and In Silico Study of some Benzylidene Hydrazide Derivatives
MI Sulistyowaty, galih putra, T Budiati… - Key Engineering …, 2020 - Trans Tech Publ
Some benzylidenehydrazides (3a-e) have been synthesized in three reaction steps from
anthranilic acid in good yields, about 70%-99%. The structures of the synthesized …
anthranilic acid in good yields, about 70%-99%. The structures of the synthesized …
Design, Synthesis, Biological Evaluation, and Molecular Docking Studies of 4‐Nitrobenzohydrazide Derivatives as Potential Anticancer Agents
A series of new acylhydrazone derivatives were synthesized from the condensation of
different substituted salicylaldehydes with 4‐nitrobenzohydrazide at a molar ratio of 1: 1 in a …
different substituted salicylaldehydes with 4‐nitrobenzohydrazide at a molar ratio of 1: 1 in a …
Design, synthesis, anti-proliferative, anti-microbial, anti-angiogenic activity and in silico analysis of novel hydrazone derivatives
Background: Cancer is the second leading cause of death globally. Hydrazone and
hydrazone derivatives have high activity, and for this reason, these compound are greatly …
hydrazone derivatives have high activity, and for this reason, these compound are greatly …
Synthesis, experimental and theoretical characterization of (E)-2-((2, 3-dimethylphenyl) amino)-N'-(furan-2-ylmethylene) benzohydrazide
Hydrazone derivatives have drawn much attention because of their large pharmacological
applications. In the present work, the compound (E)-2-((2, 3-dimethylphenyl) amino)-N' …
applications. In the present work, the compound (E)-2-((2, 3-dimethylphenyl) amino)-N' …
Synthesis, characterization, anti-proliferative activity and chemistry computation of DFT theoretical methods of hydrazine-based Schiff bases derived from methyl …
S Parvarinezhad, M Salehi - Journal of Molecular Structure, 2021 - Elsevier
In this study, the synthesized hydrazine Schiff bases belonging to methyl acetoacetate (1)
and α-hydroxyacetophenone (2) were prepared by simple methods. In addition, FT-IR, UV …
and α-hydroxyacetophenone (2) were prepared by simple methods. In addition, FT-IR, UV …
[HTML][HTML] Synthesis, anticancer, molecular docking and QSAR studies of benzoylhydrazone
To find out effective anticancer compounds we synthesized (1–30) derivatives of 4-
isopropylbenzoylhydrazone and evaluated for anticancer potential. The compounds 3, 9, 12 …
isopropylbenzoylhydrazone and evaluated for anticancer potential. The compounds 3, 9, 12 …
Synthesis, Single Crystal X-Ray, Hirshfeld Surface Analysis and DFT Calculation Based NBO, HOMO–LUMO, MEP, ECT and Molecular Docking Analysis of N′-[(2,6 …
A new Schiff base compound of N′-[(2, 6-dichlorophenyl) methylidene]-2-{[3-(trifluoro-
methyl) phenyl] amino} benzohydrazide was synthesized and characterized through various …
methyl) phenyl] amino} benzohydrazide was synthesized and characterized through various …