Following the leader: bacterial protein export through the Sec pathway
A Economou - Trends in Microbiology, 1999 - cell.com
Significant strides have been made during the past 20 years in our understanding of protein
secretion across the bacterial inner membrane. Specialized chaperones select secretory …
secretion across the bacterial inner membrane. Specialized chaperones select secretory …
Protein export through the bacterial Sec pathway
A Tsirigotaki, J De Geyter, A Economou… - Nature Reviews …, 2017 - nature.com
The general secretory (Sec) pathway comprises an essential, ubiquitous and universal
export machinery for most proteins that integrate into, or translocate through, the plasma …
export machinery for most proteins that integrate into, or translocate through, the plasma …
Protein transport across the bacterial plasma membrane by the Sec pathway
D Smets, MS Loos, S Karamanou, A Economou - The Protein Journal, 2019 - Springer
More than a third of all bacterial polypeptides, comprising the 'exportome', are transported to
extracytoplasmic locations. Most of the exportome is targeted and inserts into …
extracytoplasmic locations. Most of the exportome is targeted and inserts into …
Breaking on through to the other side: protein export through the bacterial Sec system
More than one-third of cellular proteomes traffic into and across membranes. Bacteria have
invented several sophisticated secretion systems that guide various proteins to …
invented several sophisticated secretion systems that guide various proteins to …
The extraordinary diversity of bacterial protein secretion mechanisms
IB Holland - Protein Secretion: Methods and Protocols, 2010 - Springer
I have tried to cover the minimal properties of the prolific number of protein secretion
systems identified presently, particularly in Gram negative bacteria. New systems, however …
systems identified presently, particularly in Gram negative bacteria. New systems, however …
Translocation of proteins across the cell envelope of Gram-positive bacteria
KHM van Wely, J Swaving, R Freudl… - FEMS microbiology …, 2001 - academic.oup.com
In contrast to Gram-negative bacteria, secretory proteins of Gram-positive bacteria only need
to traverse a single membrane to enter the extracellular environment. For this reason, Gram …
to traverse a single membrane to enter the extracellular environment. For this reason, Gram …
Mechanisms of protein export across the bacterial outer membrane
M Kostakioti, CL Newman, DG Thanassi… - Journal of …, 2005 - Am Soc Microbiol
Gram-negative bacteria secrete a wide range of proteins whose functions include
biogenesis of organelles, such as pili and ffagella; nutrient acquisition; virulence; and efffux …
biogenesis of organelles, such as pili and ffagella; nutrient acquisition; virulence; and efffux …
Interactions that drive Sec-dependent bacterial protein transport
SL Rusch, DA Kendall - Biochemistry, 2007 - ACS Publications
Understanding the transport of hydrophilic proteins across biological membranes continues
to be an important undertaking. The general secretory (Sec) pathway in Escherichia coli …
to be an important undertaking. The general secretory (Sec) pathway in Escherichia coli …
Bacterial secretome: the assembly manual and operating instructions
A Economou - Molecular membrane biology, 2002 - Taylor & Francis
Bacterial protein secretion is a complex multi-stage reaction that is central to membrane and
cell wall biosynthesis and essential for cell viability. An impressive array of experimental …
cell wall biosynthesis and essential for cell viability. An impressive array of experimental …
[HTML][HTML] Bacterial protein translocase: a unique molecular machine with an army of substrates
A Economou - FEBS letters, 2000 - Elsevier
Secretion of most polypeptides across the bacterial plasma membrane is catalyzed by the
Sec protein translocase. This complex molecular machine comprises a flexible …
Sec protein translocase. This complex molecular machine comprises a flexible …