Major depressive disorder (MDD) is a chronic disease that adversely affects mood and
cognition. In this study, we randomly divided the rats into control group (C), model group (M) …

Data from clinical investigations and laboratory fundings have provided preliminary
evidence for the effectiveness and safety of acupuncture therapy in depression. However …

Depression is a serious psychiatric disorder with an enormous socioeconomic burden, and it
is commonly comorbid with pain, chronic fatigue, or other inflammatory diseases. Recent …

Background The extracellular signal-regulated kinase (ERK) signaling pathway is
considered to be associated with the pathogenesis and treatment of depression …

Purpose. To explore the therapeutic efficiency of acupuncture and the related molecular
mechanism of neural plasticity in depression. Methods. Chronic unpredictable mild stress …

Acupuncture has demonstrated the function in ameliorating depressive‐like behaviors via
modulating PKA/CREB signaling pathway. To further confirm the antidepressant mechanism …

Oxidative stress is closely related to the occurrence of depression. Acupuncture has been
proved to be an effective method for treating depression. In order to explore the mechanism …

Recently, emerging evidence has identified that stress-induced activation of
neuroinflammation is considered to be one of the most prevalently precipitating factors in the …

Background Acupuncture has shown the preventive effects on depression in rats with
chronic unpredictable mild stress (CUMS). However, the mechanisms of acupuncture for …

Protein kinase A (PKA)/cAMP response element‐binding (CREB) protein signaling pathway,
contributing to impaired neurogenesis parallel to depressive‐like behaviors, has been …