Apigenin attenuates acrylonitrile-induced neuro-inflammation in rats: Involved of inactivation of the TLR4/NF-κB signaling pathway
F Zhao, Y Dang, R Zhang, G Jing, W Liang… - International …, 2019 - Elsevier
Acrylonitrile (ACN) is often found in the productions of synthetic fibers, rubber, and plastics.
Exposure to ACN could cause pathological changes of the nervous system, which appeared …
Exposure to ACN could cause pathological changes of the nervous system, which appeared …
Apigenin attenuates functional and structural alterations via targeting NF-kB/Nrf2 signaling pathway in LPS-induced parkinsonism in experimental rats: Apigenin …
M Patel, S Singh - Neurotoxicity Research, 2022 - Springer
Parkinson's disease (PD) is a progressive hypokinetic movement disorder caused by
selective degeneration of dopaminergic neurons in striatum and dopamine deficiency in a …
selective degeneration of dopaminergic neurons in striatum and dopamine deficiency in a …
Anti-neuroinflammatory effect of alantolactone through the suppression of the NF-κB and MAPK signaling pathways
L Tan, J Li, Y Wang, R Tan - Cells, 2019 - mdpi.com
Neuroinflammation is a major cause of central nervous system (CNS) damage and can
result in long-term disability and mortality. Therefore, the development of effective anti …
result in long-term disability and mortality. Therefore, the development of effective anti …
[HTML][HTML] Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer's …
NS Dourado, CS Souza, MMA De Almeida… - Frontiers in Aging …, 2020 - frontiersin.org
Neurodegenerative disorders (ND) are characterized by the progressive and irreversible
loss of neurons. Alzheimer's Disease (AD) is the most incident age-related ND, in which the …
loss of neurons. Alzheimer's Disease (AD) is the most incident age-related ND, in which the …
Anti-inflammatory and neuroprotective effect of apigenin: studies in the GFAP-IL6 mouse model of chronic neuroinflammation
Background Chronic neuroinflammation (activation of microglia and astrocytes) is a
prominent pathological process in many neurodegenerative diseases including Alzheimer's …
prominent pathological process in many neurodegenerative diseases including Alzheimer's …
The potential neuroprotective effect of allicin and melatonin in acrylamide-induced brain damage in rats
Acrylamide (ACR) is an unsaturated monomer that served various fields; however, it is a
potent neurotoxin. The target of the present study is to explore the neuroprotective efficacy of …
potent neurotoxin. The target of the present study is to explore the neuroprotective efficacy of …
Neuroprotective effect of alpha‐pinene is mediated by suppression of the TNF‐α/NF‐κB pathway in Alzheimer's disease rat model
MK Khan‐Mohammadi‐Khorrami… - … of Biochemical and …, 2022 - Wiley Online Library
Monoterpene alpha‐pinene possesses antioxidant, cardioprotective, and neuroprotective
properties. We evaluated the effect of alpha‐pinene on oxidative/nitrosative stress …
properties. We evaluated the effect of alpha‐pinene on oxidative/nitrosative stress …
The flavonoid apigenin protects brain neurovascular coupling against amyloid-β 25-35-induced toxicity in mice
R Liu, T Zhang, H Yang, X Lan… - Journal of Alzheimer's …, 2011 - content.iospress.com
Apigenin, one of the most common flavonoids, has demonstrated anti-inflammatory,
anticarcinogenic, and free radical-scavenging activities. Recent studies revealed its …
anticarcinogenic, and free radical-scavenging activities. Recent studies revealed its …
Differential inflammatory response to acrylonitrile in rat primary astrocytes and microglia
SW Caito, Y Yu, M Aschner - Neurotoxicology, 2014 - Elsevier
Acrylonitrile (ACN) is extensively used in the production of plastics, resins, nitriles and other
commercial products. Chronic low dose exposures to ACN cause glial cell tumors in rats …
commercial products. Chronic low dose exposures to ACN cause glial cell tumors in rats …
Hesperidin, an antioxidant flavonoid, prevents acrylonitrile‐induced oxidative stress in rat brain
ESM El‐Sayed, OM Abo‐Salem… - … of Biochemical and …, 2008 - Wiley Online Library
Acrylonitrile (ACN) is a volatile, toxic liquid used as a monomer in the manufacture of
synthetic rubber, styrene plastics, acrylic fiber, and adhesives. ACN is a potent neurotoxin. A …
synthetic rubber, styrene plastics, acrylic fiber, and adhesives. ACN is a potent neurotoxin. A …