Can Direct Disk Diffusion Susceptibility Testing From Positive Blood Cultures Provide Earlier Results to Clinicians?

A Desai, E Unson, M Weinstein - Open Forum Infectious …, 2016 - academic.oup.com
Background. Bloodstream infections can cause life-threatening complications. Early targeted
antimicrobial therapy is crucial to decreasing mortality and improving outcomes. Direct …

Direct susceptibility testing by disk diffusion on clinical samples: a rapid and accurate tool for antibiotic stewardship

L Coorevits, J Boelens, G Claeys - European Journal of Clinical …, 2015 - Springer
We compared the accuracy of direct susceptibility testing (DST) with conventional
antimicrobial susceptibility testing (AST), both using disk diffusion, on clinical samples. A …

[PDF][PDF] Implementation of the CLSI method for direct disk diffusion testing from positive blood cultures

AN Schuetz, A Bobenchik… - CLSI AST News Update, 2022 - community.clsi.org
The CLSI AST Subcommittee has developed and published breakpoints for direct blood
culture disk diffusion (DD) testing of several antimicrobial agents for Enterobacterales and …

Direct susceptibility testing by disk diffusion on positive BacT/ALERT blood cultures: A rapid and definite tool for antibiotic stewardship

V Lokeshwari, S Bhat, V Devi - IP International Journal of …, 2023 - researchersprofile.com
Materials and Methods: An experimental study was carried out after obtaining waiver of
consent, in a tertiary care centre. A total of 37 patients were included in the study after …

What's old is new: Leveraging existing antimicrobial susceptibility test methods for rapid results in patients with bloodstream infections

AM Prinzi - Microbiology Spectrum, 2024 - journals.asm.org
The use of rapid disk diffusion or modified automated antimicrobial susceptibility testing
(AST) system approaches demonstrates excellent performance for gram-negative organisms …

Fully automated disc diffusion for rapid antibiotic susceptibility test results: a proof-of-principle study

M Hombach, M Jetter, N Blöchliger… - Journal of …, 2017 - academic.oup.com
Background: Antibiotic resistance poses a significant threat to patients suffering from
infectious diseases. Early readings of antibiotic susceptibility test (AST) results could be of …

2168. Comparison of rapid diagnostic tests for bloodstream Infections using desirability of outcome ranking management of antimicrobial therapy (DOOR-MAT)

KC Claeys, T Hopkins, Z Kpadeh-Rogers… - Open Forum …, 2019 - academic.oup.com
Abstract Background Rapid diagnostic tests (RDTs) for bloodstream infection (BSIs) are
increasingly common. Decisions regarding which RDT to implement remains a clinical …

Rapid disc diffusion antibiotic susceptibility testing for Pseudomonas aeruginosa, Acinetobacter baumannii and Enterococcus spp.

M Hombach, M Jetter, N Blöchliger… - Journal of …, 2018 - academic.oup.com
Background We investigated the feasibility of rapid disc diffusion antibiotic susceptibility
testing (rAST) with reading of inhibition zones after 6 and/or 8 h of incubation for …

Predictive value of direct disk diffusion testing from positive blood cultures in a children's hospital and its utility in antimicrobial stewardship

TJ Savage, S Rao, J Joerger, A Ozonoff… - Journal of clinical …, 2021 - Am Soc Microbiol
Accurate and early susceptibility results could reduce overuse of broad-spectrum antibiotics
for empirical treatment of bacteremia. Direct disk diffusion testing (dDD) using …

Direct disk diffusion test using European Clinical Antimicrobial Susceptibility Testing breakpoints provides reliable results compared with the standard method

S Stokkou, G Geginat, D Schlüter… - European Journal of …, 2015 - akjournals.com
Sepsis represents a life-threatening infection requiring the immediate start of antibacterial
treatment to reduce morbidity. Thus, laboratories use direct antimicrobial susceptibility …