Regeneration of bladder urothelium, smooth muscle, blood vessels and nerves into an acellular tissue matrix

RS Sutherland, LS Baskin, SW Hayward… - The Journal of …, 1996 - auajournals.org
Purpose: To study the cellular events occurring during bladder development and
regeneration we developed an in vivo model of bladder augmentation with an acellular …

Effects of a new β3‐adrenoceptor agonist, vibegron, on neurogenic bladder dysfunction and remodeling in mice with spinal cord injury

D Gotoh, N Shimizu, N Wada… - Neurourology and …, 2020 - Wiley Online Library
Aims To examine vibegron effects on lower urinary tract dysfunction (LUTD) in mice with
spinal cord injury (SCI). Methods Female mice underwent Th8‐9 spinal cord transection and …

The role of the mucosa in modulation of evoked responses in the spinal cord injured rat bladder

C Doyle, V Cristofaro, BS Sack… - Neurourology and …, 2018 - Wiley Online Library
Aims Mounting evidence indicates that a variety of factors released from the urothelium or
suburothelium can modulate smooth muscle activity. Although the relationship between the …

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity

V Pikov, JR Wrathall - Journal of Neuroscience, 2001 - Soc Neuroscience
Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right
and may also serve as a model for studying mechanisms of functional recovery after injury in …

Nerve transfer for restoration of lower motor neuron–lesioned bladder and urethra function: establishment of a canine model and interim pilot study results

E Tiwari, DM Salvadeo, AS Braverman… - … of Neurosurgery: Spine, 2019 - thejns.org
OBJECTIVE Previous patient surveys have shown that patients with spinal cord or cauda
equina injuries prioritize recovery of bladder function. The authors sought to determine if …

Effects of liposome-based local suppression of nerve growth factor in the bladder on autonomic dysreflexia during urinary bladder distention in rats with spinal cord …

K Kadekawa, T Yoshizawa, N Wada, T Shimizu… - Experimental …, 2017 - Elsevier
Purpose To examine (1) whether spinal cord injury (SCI) time-dependently increases the
severity of autonomic dysreflexia (AD) and expression levels of bladder nerve growth factor …

Spinal stimulation of the upper lumbar spinal cord modulates urethral sphincter activity in rats after spinal cord injury

EM Abud, RM Ichiyama, LA Havton… - American Journal of …, 2015 - journals.physiology.org
After spinal cord injury (SCI), the neurogenic bladder is observed to develop asynchronous
bladder and external urethral sphincter (EUS) contractions in a condition known as detrusor …

Intravenously transplanted bone marrow stromal cells promote recovery of lower urinary tract function in rats with complete spinal cord injury

Y Hu, LM Liao, YH Ju, G Fu, HY Zhang, HX Wu - Spinal Cord, 2012 - nature.com
Objectives: There is increasing evidence that intravenously injected neural progenitor cells
promote recovery of bladder function in rodents, following contusive spinal cord injury …

Early sacral neuromodulation ameliorates urinary bladder function and structure in complete spinal cord injury minipigs

EE Keller, I Patras, I Hutu, K Roider… - Neurourology and …, 2020 - Wiley Online Library
Aims To determine the effects of early sacral neuromodulation (SNM) and pudendal
neuromodulation (PNM) on lower urinary tract (LUT) function, minipigs with complete spinal …

Reconstructed bladder innervation below the level of spinal cord injury: the knee-tendon to bladder artificial reflex arc

XY Zheng, CL Hou, HB Zhong, RS Xu… - The Journal of Spinal …, 2009 - Taylor & Francis
Abstract Background/Objective: To study the effectiveness of knee-tendon to bladder
artificial reflex arc in dogs. Methods: In 6 beagles, the proximal end of the right L5 anterior …