Genetic association between IL23R rs11209026 and rs10889677 polymorphisms and risk of Crohn's disease and ulcerative colitis: evidence from 41 studies

Y Zhu, HG Jiang, ZH Chen, BH Lu, J Li, XN Shen - Inflammation Research, 2020 - Springer
Objective IL23R plays an important role in the pathogenesis of inflammatory bowel disease
(IBD). The IL23R rs11209026 and rs10889677 polymorphisms have been shown to be …

Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist

JC Mansfield, H Holden, JK Tarlow, FS Di Giovine… - Gastroenterology, 1994 - Elsevier
Abstract Background/Aims: Ulcerative colitis and Crohn's disease have well-recognized
familial tendencies, but the genetic basis of this clinical observation remains unknown. The …

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis

EAM Festen, P Goyette, R Scott, V Annese… - Gut, 2009 - gut.bmj.com
Objectives: Genetic susceptibility is known to play a large part in the predisposition to the
inflammatory bowel diseases (IBDs) known as Crohn's disease (CD) and ulcerative colitis …

IL1B and IL1RN polymorphic genes and Helicobacter pylori cagA strains decrease the risk of reflux esophagitis

DMM Queiroz, JB Guerra, GA Rocha, AMC Rocha… - Gastroenterology, 2004 - Elsevier
Background & Aims: Proinflammatory interleukin (IL)-1 gene polymorphisms associated with
high levels of IL-1β activity increase the risk for hypochlorhydria and distal gastric …

The interleukin-8-251* T/* A polymorphism is not associated with risk for gastric carcinoma development in a Portuguese population

P Canedo, AJ Castanheira-Vale, N Lunet… - European journal of …, 2008 - journals.lww.com
It has been demonstrated that polymorphisms within inflammation-related genes are
associated with risk of gastric carcinoma in Helicobacter pylori-infected individuals …

Interleukin 1β polymorphisms increase risk of hypochlorhydria and atrophic gastritis and reduce risk of duodenal ulcer recurrence in Japan

T Furuta, EM El–Omar, F Xiao, N Shirai, M Takashima… - Gastroenterology, 2002 - Elsevier
Background & Aims: Interleukin-1 beta (IL-1β) polymorphisms are associated with increased
risk of gastric cancer in whites. This study aimed to examine effects of these polymorphisms …

IL-1 receptor antagonist (IL-1Ra) gene polymorphism in patients with inflammatory bowel disease in India

RD Mittal, HK Bid, UC Ghoshal - Scandinavian journal of …, 2005 - Taylor & Francis
Objective An association between polymorphism in the gene coding for the anti-
inflammatory cytokine interleukin-1-receptor antagonist (IL-1Ra) and ulcerative colitis (UC) …

[HTML][HTML] Association between pro-(IL-8) and anti-inflammatory (IL-10) cytokine variants and their serum levels and H. pylori-related gastric carcinogenesis in northern …

S Kumar, N Kumari, RD Mittal, S Mohindra… - Meta Gene, 2015 - Elsevier
Abstract Background Interleukin (IL)-8-251 T/A and IL-10 (-1082 G/A and-819/592 C/T)
polymorphisms and their expression may influence gastritis, atrophy, intestinal metaplasia …

Absence of a genetic association between IL-1RN and IL-1B gene polymorphisms in ulcerative colitis and Crohn disease in multiple populations from northeast …

A Craggs, S. West, A. Curtis, M. Welfare, M … - Scandinavian journal …, 2001 - Taylor & Francis
Background: Inflammatory bowel disease (IBD) is a chronic inflammation of the
gastrointestinal tract of unknown aetiology, phenotypically categorized into ulcerative colitis …

Interleukin 1B and interleukin 1RN polymorphisms are associated with increased risk of gastric carcinoma

JC Machado, P Pharoah, S Sousa, R Carvalho… - Gastroenterology, 2001 - Elsevier
Background & Aims: Interleukin (IL)-1 gene cluster proinflammatory polymorphisms have
been associated with development of gastric atrophy and with increased risk of gastric …