Resveratrol ameliorates spatial learning memory impairment induced by Aβ1–42 in rats

R Wang, Y Zhang, J Li, C Zhang - Neuroscience, 2017 - Elsevier
Abstract β-amyloid (Aβ) deposition is considered partially responsible for cognitive
dysfunction in Alzheimer's disease (AD). Recently, resveratrol has been reported to play a …

[引用][C] Bupropion and citalopram in the APP23 mouse model of Alzheimer's disease: a study in a dry-land maze

KL Neumeister, MW Riepe - International Journal of Alzheimer's Disease, 2012 - Hindawi

Amitriptyline-mediated cognitive enhancement in aged 3× Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity

W Chadwick, N Mitchell, J Caroll, Y Zhou, SS Park… - PloS one, 2011 - journals.plos.org
Approximately 35 million people worldwide suffer from Alzheimer's disease (AD). Existing
therapeutics, while moderately effective, are currently unable to stem the widespread rise in …

Low-dose delta-9-tetrahydrocannabinol as beneficial treatment for aged APP/PS1 mice

Y Wang, Y Hong, J Yan, B Brown, X Lin… - International Journal of …, 2022 - mdpi.com
Studies on the effective and safe therapeutic dosage of delta-9-tetrahydrocannabinol (THC)
for the treatment of Alzheimer's disease (AD) have been sparse due to the concern about …

Resveratrol improves cognition and decreases amyloid plaque formation in Tg6799 mice

Y Chen, GW Shi, ZM Liang… - Molecular …, 2019 - spandidos-publications.com
Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative disorder of the
central nervous system that causes severe cognitive impairment. One of the most significant …

Citalopram restores short-term memory deficit and non-cognitive behaviors in APP/PS1 mice while halting the advance of Alzheimer's disease-like pathology

Q Zhang, C Yang, T Liu, L Liu, F Li, Y Cai, K Lv, X Li… - …, 2018 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia. In addition to cognitive
impairments, deficits in non-cognitive behaviors are also common neurological sequelae in …

Restoring synaptic plasticity and memory in mouse models of Alzheimer's disease by PKR inhibition

KD Hwang, MS Bak, SJ Kim, S Rhee, YS Lee - Molecular brain, 2017 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder associated with deficits in
cognition and synaptic plasticity. While accumulation of amyloid β (Aβ) and hyper …

Tripchlorolide improves age-associated cognitive deficits by reversing hippocampal synaptic plasticity impairment and NMDA receptor dysfunction in SAMP8 mice

N Lin, X Pan, A Chen, Y Zhu, M Wu, J Zhang… - Behavioural brain …, 2014 - Elsevier
Deficits in cognition and performance accompanying age-related neurodegenerative
diseases such as Alzheimer's disease (AD) are closely associated with the impairment of …

Triptolide rescues spatial memory deficits and amyloid-β aggregation accompanied by inhibition of inflammatory responses and MAPKs activity in APP/PS1 transgenic …

YQ Cui, Q Wang, DM Zhang, JY Wang… - Current Alzheimer …, 2016 - ingentaconnect.com
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease characterized by
aggregation of amyloid-β (Aβ) peptide in the hippocampus and cortex of brain …

Tadalafil Reversed H-89–and Scopolamine–Induced Spatial Learning Impairments in Male Rats

K Tabrizian, F Amelinia, M Belaran… - Drug …, 2021 - thieme-connect.com
Accumulated evidence shows that the cAMP and cGMP signaling pathway plays an
important role in memory function and neuronal plasticity. Phosphodiesterase 5 (PDE5) is a …