Alzheimer's disease (AD) is a progressive degenerative condition. In order to treat AD, the
use of a “drug repositioning” or “repurposing” approach with potential disease-modifying …

Alzheimer's disease (AD) is a chronic progressive neurodegenerative disorder that is
associated with learning, memory, and cognitive deficits. Neuroinflammation and synapse …

Citalopram, a selective serotonin reuptake inhibitor (SSRI), is one of the most widely used
antidepressants. Recently, citalopram has been reported to improve working memory in …

Triptolide is an epoxidized diterpene lactone isolated from Tripterygium wilfordii. Studies
have shown that triptolide exerts organ‐protective effects. However, it remains unknown …

Memantine is a N-methyl-D-aspartate (NMDA) receptor antagonist approved for the
treatment of moderate to severe Alzheimer's disease (AD). Environmental enrichment (EE) …

The most prevalent type of dementia is Alzheimer's disease (AD), which is currently
incurable. Existing treatments for Alzheimer's disease, such as acetylcholinesterase …

Rationale Acetylcholinesterase inhibitors are widely used for the treatment of patients with
Alzheimer's disease (AD). However, the relationship between the capacity of such drugs to …

Alzheimer's disease (AD) is mainly characterized by the deposition of extracellular amyloid
plaques and intracellular accumulation of neurofibrillary tangles (NFTs). While the recent …

Social isolation (SI) is considered as a chronic stress. Here, middle-aged rats (8 months)
were group or isolation reared for 6 weeks. Following the initial two-week period of rearing …

The cholinesterase inhibitor donepezil is used to improve Aβ pathology and cognitive
function in patients with Alzheimer's disease (AD). However, the impact of donepezil on tau …