Emerging therapeutic targets of sepsis-associated acute kidney injury

S Swaminathan, MH Rosner, MD Okusa - Seminars in nephrology, 2015 - Elsevier
Sepsis-associated acute kidney injury (SA-AKI) is linked to high morbidity and mortality. To
date, singular approaches to target specific pathways known to contribute to the …

Update on sepsis-associated acute kidney injury: emerging targeted therapies

JF Doyle, LG Forni - Biologics: Targets and Therapy, 2016 - Taylor & Francis
Sepsis-associated acute kidney injury (SA-AKI) is an independent predictor of increased
mortality and morbidity. It is essential that further advances in the treatment of sepsis should …

[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Novel therapeutic targets for prevention and therapy of sepsis associated acute kidney injury

CH Pelte, LS Chawla - Current drug targets, 2009 - ingentaconnect.com
Sepsis associated Acute Kidney Injury (SA-AKI) is the leading cause of AKI in the hospital
setting and its incidence is increasing. Although the exact pathophysiology and phenotype …

Recent advances in the pharmacological management of sepsis-associated acute kidney injury

K Kalantari, MH Rosner - Expert Review of Clinical Pharmacology, 2021 - Taylor & Francis
Introduction Acute kidney injury is a common occurrence in patients with sepsis and
portends a high mortality as well as increased morbidity with numerous sequelae including …

Sepsis-associated acute kidney injury

CL Manrique-Caballero… - Critical Care …, 2021 - criticalcare.theclinics.com
Sepsis-associated acute kidney injury (S-AKI) is a common, life-threatening complication in
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …

Sepsis and acute kidney injury

A Zarjou, A Agarwal - Journal of the American Society of …, 2011 - journals.lww.com
Sepsis is a severe and dysregulated inflammatory response to infection characterized by
end-organ dysfunction distant from the primary site of infection. Development of acute kidney …

Sepsis-associated acute kidney injury—treatment standard

A Zarbock, JL Koyner, H Gomez… - Nephrology Dialysis …, 2024 - academic.oup.com
Sepsis is a host's deleterious response to infection, which could lead to life-threatening
organ dysfunction. Sepsis-associated acute kidney injury (SA-AKI) is the most frequent …

[HTML][HTML] Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup

A Zarbock, MK Nadim, P Pickkers, H Gomez… - Nature Reviews …, 2023 - nature.com
Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

Recent advances in pathophysiology and biomarkers of sepsis-induced acute kidney injury

I Umbro, G Gentile, F Tinti, P Muiesan, AP Mitterhofer - Journal of Infection, 2016 - Elsevier
Sepsis is a complex clinical syndrome characterized by a systemic inflammatory response to
an infective insult. This process often leads to widespread tissue injury and multiple organ …