Septic acute kidney injury (AKI) occurs between 15% and 20% of all intensive care unit
admissions and its mortality ranges from 20% to 60%. The incidence and mortality of septic …

Objective: Sepsis is the most common cause of acute kidney injury in critically ill patients;
however, the mechanisms leading to acute kidney injury in sepsis remain elusive. Although …

Acute kidney injury (AKI) is common in critically ill children and adults, and sepsis-
associated AKI (SA-AKI) is the most frequent cause of AKI in the ICU. To date, no …

Given that the leading clinical conditions associated with acute kidney injury (AKI), namely,
sepsis, major surgery, heart failure, and hypovolemia, are all associated with shock, it is …

Inflammation and coagulation are critical self-defense mechanisms for mitigating infection
that can nonetheless induce tissue injury and organ dysfunction. In severe cases, like …

Objective To review the unique pathophysiology of sepsis‐induced acute kidney injury (AKI)
and highlight the relevant aspects of the Kidney Disease: Improving Global Outcomes …

Many of the common severe illnesses, including sepsis and septic shock, severe trauma,
burns or other overwhelming stresses, are characterized by the widespread activation of …

Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …

The incidence and mortality of sepsis and the associated development of acute kidney injury
(AKI) remain high, despite intense research into potential treatments. Targeting the …

Background Due to the high incidence and mortality of sepsis-associated acute kidney
injury, a significant number of studies have explored the causes of sepsis-associated acute …