Sepsis is the leading cause of acute kidney injury (AKI) and leads to increased morbidity
and mortality in intensive care units. Current treatments for septic AKI are largely supportive …

Sepsis is a dynamic state that progresses at variable rates and has life-threatening
consequences. Staging patients along the sepsis timeline requires a thorough knowledge of …

Evidence is accumulating showing that septic acute kidney injury (AKI) is different from non-
septic AKI. Specifically, a large body of research points to apoptotic processes underlying …

Sepsis is one of the most common reasons for critically ill patients to be admitted to an
intensive care unit and, despite advances in overall medical care, it represents a major …

Sepsis, an infection‐induced systemic disease, leads to pathological, physiological, and
biochemical abnormalities in the body. Organ dysfunction is caused by a dysregulated host …

Acute kidney injury (AKI) is a multifactorial syndrome with a complex pathophysiology
including different inflammatory cells and mediators. Current research focuses on identifying …

Purpose To provide an overview of current literature on the pathophysiology of sepsis, with a
focus on mediators of endothelial injury and organ dysfunction. Summary Sepsis is a …

Severe sepsis is among the most common causes of death in the United States and the most
common cause of death in the Intensive Care Units worldwide, and its recognition and …

Sepsis-associated acute kidney injury (SA-AKI) is a major issue in medical, surgical and
intensive care settings and is an independent risk factor for increased mortality, as well as …

Background Despite advances in medical technologies and intervention occurrences, acute
kidney injury (AKI) incidence continues to rise. Early interventions after sepsis are essential …