To explore the possibility that dopa and 5-S-cysteinyldopa, precursors of melanin, can be
produced in non-melanogenic tissues, this study examined the contents of the free and …

Free dopa and 5-S-cysteinyldopa were extracted from two human melanomas. Subsequent
hydrolysis of carefully washed melanoma tissue released dopa and 5-S-cysteinyldopa …

This study examined how various genotypes of coat color in mice and guinea pigs are
related to the type and content of melanin and to the levels of free and protein-bound dopa …

Dopa and 5-S-cysteinyldopa levels in serum of albino, red, and black guinea-pigs were
quantified. The levels of both amino acids were lower in the albino than in the pigmented …

Dear Sir, In mice,> 120 genes are involved in the development, proliferation and
differentiation of epidermal melanocytes, and more than half of those genes have been …

The hypothesis that only melanosomal catecholic amino acids contribute to melanin
formation was tested by studying adult bovine eyes in which pigment synthesis is …

The urine of an albino woman contained small quantities of 5-S-cysteinyldopa; 6-hydroxy-5-
methoxyindole-2-carboxylic acid, a melanin precursor metabolite, was lacking. The 5-S …

Cbromatography and fluorimetric analysis of urine extracts of healthy subjects revealed the
prescnce of two catechol derivatives with the characteristics of dopa and 5-S-cysteinyldopn …

lncorporation of L-dopa, L-! X• methyl dopa and OL• i oproterenol 1nto the hair of blac
p1gmentcd guinca pigs was measurcd by a 3H-tracer method. These drugs wcre found to be …

Abstract Melanin formation from 3, 4-dihydroxyphenylalanine (dopa) was studied in the
presence of estradiol and 2-hydroxyestradiol by use of a tyrosinase isolated from B16-F10 …