Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content

BH Goodpaster, DE Kelley… - Journal of applied …, 2000 - journals.physiology.org
The purpose of this investigation was to validate that in vivo measurement of skeletal muscle
attenuation (MA) with computed tomography (CT) is associated with muscle lipid content …

Muscle‐associated triglyceride measured by computed tomography and magnetic resonance spectroscopy

DE Larson‐Meyer, SR Smith, LK Heilbronn… - …, 2006 - Wiley Online Library
Objective: Muscle triglyceride can be assessed in vivo using computed tomography (CT)
and 1H magnetic resonance spectroscopy (MRS), two techniques that are based on entirely …

Composition of skeletal muscle evaluated with computed tomography

BH Goodpaster, FL Thaete… - Annals of the New York …, 2000 - Wiley Online Library
Computed tomography (CT) can yield quantitative imaging data from detailed maps of linear
attenuation coefficients within tissue. The attenuation characteristics of skeletal muscle and …

Measurement of skeletal muscle radiation attenuation and basis of its biological variation

J Aubrey, N Esfandiari, VE Baracos… - Acta …, 2014 - Wiley Online Library
Skeletal muscle contains intramyocellular lipid droplets within the cytoplasm of myocytes as
well as intermuscular adipocytes. These depots exhibit physiological and pathological …

Intramuscular lipid content is increased in obesity and decreased by weight loss

BH Goodpaster, R Theriault, SC Watkins, DE Kelley - Metabolism, 2000 - Elsevier
The triglyceride content of skeletal muscle samples determined by lipid extraction correlates
with the severity of insulin-resistant glucose metabolism in muscle. To determine whether …

Skeletal muscle triglyceride levels are inversely related to insulin action

DA Pan, S Lillioja, AD Kriketos, MR Milner, LA Baur… - Diabetes, 1997 - Am Diabetes Assoc
In animal studies, increased amounts of triglyceride associated with skeletal muscle (mTG)
correlate with reduced skeletal muscle and whole body insulin action. The aim of this study …

[HTML][HTML] Skeletal muscle lipid concentration quantified by magnetic resonance imaging

BH Goodpaster, VA Stenger, F Boada… - The American journal of …, 2004 - Elsevier
Background Skeletal muscle lipid is associated with obesity and type 2 diabetes and may be
altered by diet, physical activity, and weight loss. Objective We explored the utility of …

Regional differences in intramyocellular lipids in humans observed by in vivo 1H-MR spectroscopic imaging

JH Hwang, JW Pan, S Heydari… - Journal of Applied …, 2001 - journals.physiology.org
Regional differences in the content of intramyocellular lipids (IMCL), extramyocellular lipids,
and total creatine (TCr) were quantified in soleus (S), tibialis posterior (TP), and tibialis …

Attenuation of skeletal muscle and strength in the elderly: The Health ABC Study

BH Goodpaster, CL Carlson, M Visser… - Journal of applied …, 2001 - journals.physiology.org
Although loss of muscle mass is considered a cause of diminished muscle strength with
aging, little is known regarding whether composition of aging muscle affects strength. The …

Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women

JA Simoneau, SR Colberg, FL Thaete… - The FASEB …, 1995 - Wiley Online Library
Regional fat distribution is an important determinant of insulin resistance in obesity. In the
current study, the relationship between skeletal muscle insulin sensitivity, mid‐thigh muscle …