Chemoprevention represents a highly promising approach for the control of cancer. That
nonsteroidal anti-inflammatory drugs (NSAIDs) prevent colon and other cancers has led to …

The seminal epidemiological observation that nonsteroidal anti-inflammatory drugs
(NSAIDs) prevent colon and possibly other cancers has spurred novel approaches to cancer …

NSAIDs (non-steroidal anti-inflammatory drugs) prevent colon and other cancers. The fact
that NSAIDs inhibit the eicosanoid pathway prompted mechanistic drug-developmental work …

Epidemiological and clinical studies suggest that non-steroidal anti-inflammatory drugs
(NSAIDs), including cyclooxygenase (COX)-2 selective inhibitors, reduce the risk of …

Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

Arachidonic acid metabolism through cyclooxygenase (COX) pathways leads to the
generation of biologically active eicosanoids. Eicosanoid expression levels vary during …

Various clinical and epidemiologic studies show that nonsteroidal anti-inflammatory drugs
(NSAIDs), including aspirin and cyclooxygenase inhibitors (COXIBs) help prevent cancer …

Cyclooxygenase (COX)-2, an inducible enzyme involved in prostaglandin biosynthesis, has
attracted considerable attention recently, due to its role in human cancer biology. Several …

Background Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to have
antitumor effects in various systems including in vitro cell cultures of human cancer cell lines …

There is compelling evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) and
cyclooxygenase-2 selective inhibitors have antineoplastic activity, but toxicity from …