Does glutamine promote benefits for patients with diabetes mellitus scheduled for cardiac surgery?

VV Lomivorotov, SM Efremov, VA Shmirev… - Heart, Lung and …, 2013 - Elsevier
BACKGROUND: We hypothesised, that perioperative use of N (2)-l-alanyl-l-glutamine
confers cardioprotection and improves insulin resistance in diabetic patients with coronary …

Glutamine is cardioprotective in patients with ischemic heart disease following cardiopulmonary bypass

VV Lomivorotov, SM Efremov, VA Shmirev… - The heart surgery …, 2011 - journal.hsforum.com
Background: The aim of the present study was to investigate the cardioprotective effects of
the perioperative use of N (2)-L-alanyl-L-glutamine (GLN) in patients with ischemic heart …

Efficacy of Perioperative Infusion of N (2)-L-alanyl-L-glutamine in Glycemic Control for Patients with Uncontrolled Diabetes Mellitus Presented for Urgent Coronary …

AHM Ahmad, FK Eldin, MM Rashed - Journal of Cardiothoracic and …, 2023 - Elsevier
Objectives To evaluate the efficacy of preoperative glutamine infusion in reducing insulin
requirements in patients with uncontrolled type 2 diabetes, defined as glycated hemoglobin …

Myocardial protecting role of glutamine in patients with low ejection fraction undergoing elective on-pump coronary artery bypass graft surgery

IMA Parmana, CE Boom, L Rachmadi… - Vascular Health and …, 2022 - Taylor & Francis
Purpose Myocardial injury due to on-pump coronary artery bypass grafting (CABG) in
patients with low ejection fraction (EF) is associated with poor outcomes. This study …

[HTML][HTML] Preoperative glutamine infusion improves glycemia in heart surgery patients

MN Hissa, RC Vasconcelos, SB Guimarães… - Acta Cirurgica …, 2011 - SciELO Brasil
PURPOSE: To evaluate the effects of pre-operative L-alanyl-glutamine (L-Ala-Gln) on blood
glucose control in patients with coronary obstruction, selected for myocardial …

[HTML][HTML] Glutamate Infusion Reduces Myocardial Dysfunction after Coronary Artery Bypass Grafting According to NT-proBNP: Summary of 2 Randomized Controlled …

J Holm, F Vanky, R Svedjeholm - The American Journal of Clinical Nutrition, 2023 - Elsevier
Background Glutamate is reported to enhance the recovery of oxidative metabolism and
contractile function of the heart after ischemia. The effect appears to be blunted in diabetic …

The supportive value of pre-bypass L-glutamate loading in patients undergoing coronary artery bypass grafting

G Bitzikas, C Papakonstantinou… - Journal of …, 2005 - search.proquest.com
AIM: Experimental studies have demonstrated that an exogenous supply of glutamate
improves mechanical function and recovery of ischemic myocardium. The aim of the present …

Pharmacologically dosed oral glutamine reduces myocardial injury in patients undergoing cardiac surgery: a randomized pilot feasibility trial

A Sufit, LB Weitzel, C Hamiel… - Journal of Parenteral …, 2012 - Wiley Online Library
Background and Objective: Glutamine (GLN) has been shown to protect against in vitro and
in vivo myocardial injury. In humans, perioperative ischemia/reperfusion (I/R) injury during …

The effect of glutamate infusion on cardiac performance is independent of changes in metabolism in patients undergoing routine coronary artery bypass surgery

CJ LANGENBERG, HG PIETERSEN… - Clinical …, 2001 - portlandpress.com
In a double-blind randomized placebo-controlled study, the effects of intravenous glutamate
infusion on myocardial haemodynamics and metabolism were studied in 22 patients …

Effects of preoperative intravenous glutamine administration on cardiac and renal functions in patients undergoing mitral valve replacement surgeries: A randomized …

M F. Mostafa, H Ahmad Ibrahim Elmorabaa… - Egyptian Journal of …, 2023 - Taylor & Francis
Background Preoperative poor nutrition greatly raises the risk of complications and
increases length of stay (LOS). Glutamine deficiency may impair immune functions, reduce …