Apoptosis was originally defined in mammals, where it plays a major role in controlling
normal development. Apoptosis and several other forms of programmed cell death (PCD) …

Recent findings have revealed the role of prion-like mechanisms in the control of host
defense and programmed cell death cascades. In fungi, HET-S, a cell death-inducing …

Hexokinases catalyse the first step in glucose metabolism and play a role in glucose
sensing in mammals, plants and fungi. We describe a new class of hexokinases that appear …

Apoptosis is one type of programmed cell death with great importance for development and
homeostasis of multicellular organisms. Unexpectedly, during the past decade, evidence …

''By the time I was born, more of me had died than survived. It was no wonder I cannot
remember; during that time I went through brain after brain for nine months, finally contriving …

Recent findings suggest a pivotal role for mitochondria-associated hexokinase in the
regulation of apoptosis in animal cells. In this study, virus-induced gene silencing (VIGS) of a …

Death is an important part of an organism's existence and also marks the end of life. On a
cellular level, death involves the execution of complex processes, which can be classified …

Programmed cell death (PCD), in which cells actively participate in their own death through
the activation of defined pathways, has long been established as an important …

As opposed to single-cell yeast and mammalian cell lines, apoptosis has not been greatly
investigated in filamentous fungi because antibodies to the relevant fungal apoptosis-related …

Upon apoptosis induction, translocation of mammalian mitochondrial endonuclease G
(EndoG) to the nucleus coincides with large-scale DNA fragmentation. Here, we describe for …