The plant response to attempted infection by microbial pathogens is often accompanied by
rapid cell death in and around the initial infection site, a reaction known as the …

The genome from Neurospora crassa presented three open reading frames homologous to
the genes coding for human AIF and AMID proteins, which are flavoproteins with …

Plants have evolved distinct pathways and strategies from those of animals to cope with
environmental stresses as well as microbial invaders. This is in part due to the sessile nature …

The cell wall integrity (CWI) signaling pathway is best known for its roles in cell wall
biogenesis. However, it is also thought to participate in the response to genotoxic stress. The …

We recently showed that activated Ras proteins are localized to the plasma membrane and
in the nucleus in wild-type cells growing exponentially on glucose, while in the hxk2Δ strain …

Chk1 is a protein kinase that acts as a key signal transducer within the complex network
responsible of the cellular response to different DNA damages. It is a conserved element …

Programmed cell death (PCD) is an integral part of the development and survival of all
multicellular organisms. Over the past decade, key regulators of apoptosis (the best …

The mechanism of p53-dependent apoptosis is still only partly defined. Using early-passage
embryonic fibroblasts (MEF) from wild-type (wt), p53−/− and bax−/− mice, we observe a p53 …

The shared features between plant and animal programmed cell death are becoming
increasingly apparent. In this study, human Bcl-2, an anti-apoptotic member of the Bcl-2 …

In a large group of fungi, mating results in a dikaryon, a cell in which the two nuclei-one from
each parent cell-share a single cytoplasm for a period of time without undergoing nuclear …