Advanced glycation end‐products (AGE s) play a role in the pathophysiology of diabetes
mellitus (DM) and possibly hypertension (HTN). In experimental DM, AGE s accumulate in …

Advanced glycation end-products (AGEs) result from oxidation–reduction reactions that
ensue when a sugar becomes adducted to a protein. AGEs cause various complications of …

Background Heart failure is associated with abnormalities of myocardial structure, and
plasma levels of the advanced glycation end-product (AGE) Nε-(carboxymethyl) lysine …

Heart disease is one of the most important causes of death in developed countries. N ε-
carboxymethyllysine (CML) is a major advanced glycation end product formed by combined …

Objective Advanced glycation end products (AGEs) are known to play important roles in the
development of diabetes mellitus and atherosclerosis. N ε-(carboxymethyl) lysine (CML) is …

Heart failure is a condition closely linked to diabetes. Hyperglycaemia amplifies the
generation of a major advanced glycation end product Nε-(carboxymethyl) lysine (CML) …

Objective—Advanced glycation end products (AGEs), such as Nε-(carboxymethyl) lysine
(CML), are implicated in vascular disease. We previously reported increased CML …

Background: An important role in the acceleration of vascular disease has been previously
suggested for advanced glycation end products. N ε-(carboxymethyl) lysine (CML) is an …

Myocardial dysfunction in the absence of myocardial ischemia is frequent in patients with
diabetes mellitus but the underlying pathomechanism is unclear. We investigated whether …

N (epsilon)-(Carboxymethyl) lysine (CML), a major product of oxidative modification of
glycated proteins, has been suggested to represent a general marker of oxidative stress and …