Women and research on cardiovascular diseases in Europe: a report from the European Heart Health Strategy (EuroHeart) project

M Stramba-Badiale - European Heart Journal, 2010 - academic.oup.com
Cardiovascular diseases represent the major cause of mortality in women and in men. 1, 2
However, gender differences in the clinical presentation of cardiovascular diseases have …

Sex bias is increasingly prevalent in preclinical cardiovascular research: implications for translational medicine and health equity for women: a systematic assessment …

FD Ramirez, P Motazedian, RG Jung, P Di Santo… - Circulation, 2017 - Am Heart Assoc
Sex Bias Is Increasingly Prevalent in Preclinical Cardiovascular Research: Implications for
Translational Medicine and Health Equity for Women | Circulation Science Volunteer Warning …

A systematic review on pharmacogenetics in cardiovascular disease: is it ready for clinical application?

JJW Verschuren, S Trompet, JAM Wessels… - European heart …, 2012 - academic.oup.com
Pharmacogenetics is the search for heritable genetic polymorphisms that influence
responses to drug therapy. The most important application of pharmacogenetics is to guide …

[HTML][HTML] Age and sex in drug development and testing for adults

C Tannenbaum, D Day - Pharmacological research, 2017 - Elsevier
Individualization of drug therapy requires that the right drug be administered at the correct
dose to patients who are likely to achieve the highest benefit and lowest risk. Female sex …

Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and …

C Perrino, P Ferdinandy, HE Bøtker… - Cardiovascular …, 2021 - academic.oup.com
Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and
morbidity in both men and women. Sex, however, affects several aspects of IHD, including …

Sex-specific differences in side effects of psychotropic drugs: genes or gender?

S Haack, A Seeringer, PA Thürmann, T Becker… - …, 2009 - Future Medicine
Sex differences observed in the adverse effects associated with psychotropic drugs have not
been reported consistently in the literature. In this review, we discuss the current published …

Illuminating the mechanisms underlying sex differences in cardiovascular disease

K Reue, CB Wiese - Circulation research, 2022 - Am Heart Assoc
Sex is a key risk factor for many types of cardiovascular disease. It is imperative to
understand the mechanisms underlying sex differences to devise optimal preventive and …

Gender-based research underscores sex differences in biological processes, clinical disorders and pharmacological interventions

SR Bernstein, C Kelleher, RA Khalil - Biochemical Pharmacology, 2023 - Elsevier
Earlier research has presumed that the male and female biology is similar in most organs
except the reproductive system, leading to major misconceptions in research interpretations …

Ethnicity and psychopharmacology

IB Chaudhry, K Neelam, V Duddu… - Journal of …, 2008 - journals.sagepub.com
Ethnicity is reported to be an important, but often ignored factor in psychopharmacology.
However, recent advances in molecular biology and the vision of'personalised …

[HTML][HTML] Sex-related differences in pharmacological response to CNS drugs: a narrative review

M Romanescu, V Buda, A Lombrea, M Andor… - Journal of Personalized …, 2022 - mdpi.com
In the last decades, both animal and human studies have neglected female subjects with the
aim of evading a theorized intricacy of feminine hormonal status. However, clinical …