Systematic review: the safety of vedolizumab for the treatment of inflammatory bowel disease

WA Bye, V Jairath, SPL Travis - Alimentary pharmacology & …, 2017 - Wiley Online Library
Background Vedolizumab specifically recognises the α4β7 integrin and selectively blocks
gut lymphocyte trafficking: potentially, it offers gut‐specific immunosuppression. Aim To …

[HTML][HTML] Efficacy and safety of vedolizumab for inflammatory bowel diseases: a systematic review and meta-analysis of randomized controlled trials

B Qiu, JX Liang, C Li - Medicine, 2022 - journals.lww.com
Background: Vedolizumab is a humanized monoclonal antibody that inhibits gut-selective
α4β7 integrins on the surface of leukocytes, preventing their trafficking into the …

[HTML][HTML] A product review of vedolizumab in inflammatory bowel disease

R Battat, PS Dulai, V Jairath… - Human vaccines & …, 2019 - Taylor & Francis
Vedolizumab is a monoclonal antibody to the α4β7 integrin that selectively reduces
intestinal lymphocyte trafficking, thereby providing a safe and effective treatment option for …

Long‐term safety of vedolizumab for inflammatory bowel disease

EV Loftus Jr, BG Feagan, R Panaccione… - Alimentary …, 2020 - Wiley Online Library
Background Vedolizumab, a gut‐selective α4β7 integrin antibody, is approved for
moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD). Aim To report …

Low frequency of opportunistic infections in patients receiving vedolizumab in clinical trials and post-marketing setting

SC Ng, IN Hilmi, A Blake, F Bhayat… - Inflammatory Bowel …, 2018 - academic.oup.com
Background Vedolizumab (ENTYVIO) is a humanized α4β7 integrin antagonist approved for
the treatment of inflammatory bowel disease, which selectively blocks gut-specific …

Introducing vedolizumab to clinical practice: who, when, and how?

RV Bryant, WJ Sandborn… - Journal of Crohn's and …, 2015 - academic.oup.com
Vedolizumab (VDZ), a humanized monoclonal antibody that selectively targets α4β7
integrin, is approved for use in inflammatory bowel disease (IBD). Here we review the …

An update on the safety of long-term vedolizumab use in inflammatory bowel disease

S Honap, P Netter, S Danese… - Expert Opinion on Drug …, 2023 - Taylor & Francis
ABSTRACT Introduction Vedolizumab (Entyvio) is a humanized monoclonal antibody that
disrupts the interaction between α4β7 integrin on circulating T-lymphocytes and MAdCAM-1 …

[HTML][HTML] PRISMA—efficacy and safety of vedolizumab for inflammatory bowel diseases: a systematic review and meta-analysis of randomized controlled trials

MC Wang, LY Zhang, W Han, Y Shao, M Chen, R Ni… - Medicine, 2014 - journals.lww.com
PRISMA—Efficacy and Safety of Vedolizumab for Inflammatory B... : Medicine PRISMA—Efficacy
and Safety of Vedolizumab for Inflammatory Bowel Diseases: A Systematic Review and …

The safety of vedolizumab for ulcerative colitis and Crohn's disease

JF Colombel, BE Sands, P Rutgeerts, W Sandborn… - Gut, 2017 - gut.bmj.com
Objective Vedolizumab is a gut-selective antibody to α4β7 integrin for the treatment of
ulcerative colitis (UC) and Crohn's disease (CD). We report an integrated summary of the …

Postoperative outcomes in vedolizumab-treated patients undergoing abdominal operations for inflammatory bowel disease

AL Lightner, LE Raffals, KL Mathis… - Journal of Crohn's …, 2017 - academic.oup.com
Introduction: Vedolizumab was recently approved by the Food and Drug Administration for
the treatment of moderate to severe ulcerative colitis [UC] and Crohn's disease [CD]. No …